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http://www.souku.com.cn/viewtitle.jsp?url=3771242 CAS登记号：106-89-8----化学品毒性数据库 [ Last edited by zzgyb on 2008-7-22 at 08:35 ] |
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106-89-8 *** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TX4900000 CHEMICAL NAME : Propane, 1-chloro-2,3-epoxy- CAS REGISTRY NUMBER : 106-89-8 BEILSTEIN REFERENCE NO. : 0079785 REFERENCE : 5-17-01-00020 (Beilstein Handbook Reference) LAST UPDATED : 199801 DATA ITEMS CITED : 144 MOLECULAR FORMULA : C3-H5-Cl-O MOLECULAR WEIGHT : 92.53 WISWESSER LINE NOTATION : T3OTJ B1G COMPOUND DESCRIPTOR : Agricultural Chemical Tumorigen Mutagen Reproductive Effector Human Primary Irritant SYNONYMS/TRADE NAMES : * 1-Chloor-2,3-epoxy-propaan * 1-Chlor-2,3-epoxy-propan * 1-Chloro-2,3-epoxypropane * 3-Chloro-1,2-epoxypropane * 1-Chloro-2,3-epoxypropane * epi-Chlorohydrin * (Chloromethyl)ethylene oxide * Chloromethyloxirane * 2-(Chloromethyl)oxirane * 3-Chloro-1,2-propane oxide * Chloropropylene oxide * gamma-Chloropropylene oxide * 3-Chloro-1,2-propylene oxide * 1-Cloro-2,3-epossipropano * ECH * Epichloorhydrine * Epichlorhydrin * Epichlorhydrine * Epichlorohydrin * alpha-Epichlorohydrin * (DL)-alpha-Epichlorohydrin * Epichlorohydryna * Epichlorophydrin * Epicloridrina * 1,2-Epoxy-3-chloropropane * 2,3-Epoxypropyl chloride * Glycerol epichlorhydrin * Oxirane, (chloromethyl)- * Oxirane, 2-(chloromethyl) * RCRA waste number U041 * Skekhg *** HEALTH HAZARD DATA *** ** SKIN/EYE IRRITATION DATA ** TYPE OF TEST : Open irritation test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 10 mg/24H REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 100 mg REACTION SEVERITY : Severe REFERENCE : AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 100 mg/24H REACTION SEVERITY : Moderate REFERENCE : 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,769,1986 ** ACUTE TOXICITY DATA ** TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Human DOSE/DURATION : 40 ppm/2H TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes REFERENCE : 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,240,1969 TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Human DOSE/DURATION : 20 ppm TOXIC EFFECTS : Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Sense Organs and Special Senses (Eye) - effect, not otherwise specified REFERENCE : 29ZWAE "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968 Volume(issue)/page/year: -,108,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 90 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 ppm/8H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,41,1974 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes Skin and Appendages - hair REFERENCE : UCPHAQ University of California, Berkeley, Publications in Pharmacology. (Berkeley, CA) V.1-3, 1938-57. Discontinued. Volume(issue)/page/year: 2,69,1941 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 133 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 52,422,1980 |
5楼2008-06-06 17:29:11
我是一只小马甲
铁杆木虫 (知名作家)
明天跟xww去肯尼亚放牛
- 应助: 18 (小学生)
- 贵宾: 0.01
- 金币: 9782.6
- 散金: 3000
- 红花: 12
- 帖子: 6487
- 在线: 332小时
- 虫号: 439076
- 注册: 2007-10-07
3楼2008-06-06 17:05:32
我是一只小马甲
铁杆木虫 (知名作家)
明天跟xww去肯尼亚放牛
- 应助: 18 (小学生)
- 贵宾: 0.01
- 金币: 9782.6
- 散金: 3000
- 红花: 12
- 帖子: 6487
- 在线: 332小时
- 虫号: 439076
- 注册: 2007-10-07
4楼2008-06-06 17:07:25
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TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - urine volume increased REFERENCE : AMPMAR Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. (SPPIF, B.P.22, F-41353 Vineuil, France) V.7- 1946- Volume(issue)/page/year: 28,505,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 154 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,41,1974 |
6楼2008-06-06 17:29:46
