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zolpidem disrupted the pattern of wakefulness and induced sleep periods of short duration with doses of 0.1 mg/kg i.p.(or 0.3 mg/kg p.o., data not shown). At 0.3 and 1 mg/kg i.p£¬zolpidem induced large slow waves sleep with some bursts of sleep spindles at 12-- 14 Hz, particularly in the sensorimotor cortex¡£ Power spectral analysis of the electrocorticogram recordings with increasing doses of zolpidem (0.1 to 1 mg/kg i.p.), showed fast onset transient increases in the energy of the frequency bands I to 16 Hz with a dominant 2-3 Hz peak in the delta frequency band (1-4Hz). |
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xiaowanzi9: ½ð±Ò+15, ·ÒëEPI+1, ¡ï¡ï¡ï¡ï¡ï×î¼Ñ´ð°¸, O(¡É_¡É)Oлл 2014-12-09 13:39:19
xiaowanzi9: ½ð±Ò+15, ·ÒëEPI+1, ¡ï¡ï¡ï¡ï¡ï×î¼Ñ´ð°¸, O(¡É_¡É)Oлл 2014-12-09 13:39:19
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