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[资源] 药物晶型最经典参考书 Polymorphism in Pharmaceutical Solids_Second Edition

Sample Text
James Swarbrick
PharmaceuTech, Inc.
Pinehurst, North Carolina

PART I    THERMODYNAMIC AND THEORETICAL ISSUES
1. Theory and Principles of Polymorphic Systems
2. Application of the Phase Rule to the Characterization
of Polymorphic and Solvatomorphic Systems
3. Computational Methodologies: Toward Crystal Structure
and Polymorph Prediction

PART II  PREPARATIVE METHODS FOR POLYMORPHS
AND SOLVATOMORPHS
4. Classical Methods of Preparation of Polymorphs
and Alternative Solid Forms
5. Approaches to High-Throughput Physical Form
Screening and Discovery

PART III  STRUCTURAL PROPERTIES OF POLYMORPHS
AND SOLVATOMORPHS
6. Structural Aspects of Polymorphism
7. Structural Aspects of Solvatomorphic Systems
8. Pharmaceutical Co-crystals: A New Opportunity in Pharmaceutical Science for a Long-Known but Little-S
Class of Compounds

PART IV  CHARACTERIZATION METHODS FOR POLYMORP
AND SOLVATOMORPHS
9. Thermoanalytical and Crystallographic Methods
10. Vibrational Spectroscopy
11. Solid-State Nuclear Magnetic Resonance Spectroscopy
Patrick A. Tishmack
12. Effects of Polymorphism and Solid-State Solvation
on Solubility and Dissolution Rate

PART V INTERCONVERSION OF POLYMORPHS AND SOLV
13. Solid-State Phase Transformations
14. Effects of Pharmaceutical Processing on the Solid Form
of Drug and Excipient Materials

PART VI  SPECIAL TOPICS RELATED TO POLYMORPHISM
AND SOLVATOMORPHISM
15. Structural Aspects of Molecular Dissymmetry
16. Amorphous Solids

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2014-11-22 20:11:34, 11.02 M