| 查看: 424 | 回复: 1 | |||
| 本帖产生 1 个 翻译EPI ，点击这里进行查看 | |||
[求助]
求快速翻译
|
|||
|
As using optically pure L-phenylalanine as starting material, so we suggested that all of these palladium complexes were chiral because the chiral center would survive in all the experimental process. The X-ray structure of 3a and 3c confirmed there is a stereogenic center with S configuration in the back bone of imidazoline ring. The specific rotation of these Pd complexes in DCM is 6.3 ° for 3a; 104.8 ° for 3b; 78.9 ° for 3c and 72.4 ° for 3d. To evaluate the catalytic activity of 3a-3d in the Cu-free Sonogashira coupling reactions under aerobic conditions, we performed the reaction of 1-iodo-2-methoxybenzene with phenylacetylene in DMSO in presence of K2CO3 as base at 100 oC for 1 h, using 1 mol % catalyst loading. As it can be seen from the results shown in Table 2 (entries 1-4), complex 3a is the one that provides the best activity (69% yield), whereas the other complexes (3b-3d) do not show good activity, especially 3d leading to only 31% yield.  [C[NG5B2HOHWAGHU4XUSUWA.jpg  1`{KFF5ZLUS4E`D1MNM32F9.jpg |
回复此楼» 猜你喜欢
2025年遐想
已经有5人回复
-
论文终于录用啦！满足毕业条件了
已经有12人回复
-
投稿Elsevier的杂志（返修），总是在选择OA和subscription界面被踢皮球
已经有8人回复
-
求个博导看看
已经有18人回复
ssssllllnnnn 
至尊木虫 (知名作家)
Translator and Proofreader
- 翻译EPI: 1690
- 应助: 452 (硕士)
- 金币: 31580.9
- 红花: 100
- 帖子: 7681
- 在线: 19966.6小时
- 虫号: 3328089
- 注册: 2014-07-17
- 专业: 肿瘤发生
【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★
嗜血风铃: 金币+20, 翻译EPI+1, ★★★很有帮助, good 2014-11-04 10:11:48
嗜血风铃: 金币+20, 翻译EPI+1, ★★★很有帮助, good 2014-11-04 10:11:48
|
因为使用了光学纯的L-苯丙氨酸为起始原料，所以我们认为所有这些钯复合物都是是手性的，因为手性中心可以在所有的实验过程中存留下来。3a和3c的X-射线结构证在咪唑啉环的主链有一具有S构型的手性中心。在DCM这些钯复合物的比旋光度为：3a是6.3°; 3b是104.8°; 3c是78.9°；3d是72.4°。 在有氧而无铜的条件下，用Sonogashira偶联反评价了3a-3d的催化活性。反应用1-碘-2-甲氧基苯和苯乙炔在DMSO中进行，用K2CO3提供碱，在100℃反应1小时，使用1％摩尔的催化剂负载量。从表2结果（条目1-4）可以看出，复合3a的活性活性最佳（产率69％），而其他复合物（3b〜3d）都不具有出良好的活性，特别是3d只引起31％的产率。 |
2楼2014-11-04 09:14:30