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A new series of chiral N-heterocyclic carbene (NHC) palladium complexes were synthesized from
relatively inexpensive amino acid, L-phenylalanine. All these compounds were fully characterized by 1HNMR,
13C-NMR and Element analysis. The X-ray molecular structures of two of the complexes were
reported. The catalytic activity of the four palladium complexes was successfully tested in the
Sonogashira reaction under copper free conditions in air. The palladium complex 3a provided good
activity in the Sonogashira coupling reaction.

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