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关于线粒体靶向,线粒体膜电位
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The delocalization of the positive charge reduces the activation energy associated with desolvating the ion that must occur prior to its uptake through the hydrophobic IMM The positive charge is spread over a large surface area in order to increase its ionic radius, effectively reducing the interaction with surrounding water molecules.24 These features allow such molecules to partition across the IMM driven by its large negative potential dictated by the Nernst equation |
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