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dennistt

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DOI: 10.1016/j.jtice.2013.12.004
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muse

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2楼2014-09-23 19:20:42
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muse

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Optimization for the extraction of polysaccharides from Gentiana scabra Bunge and their antioxidant in vitro and anti-tumor activity in vivo

作者:Wang, CY (Wang, Chenyu)[ 1 ] ; Wang, Y (Wang, Yan)[ 2 ] ; Zhang, J (Zhang, Jing)[ 1 ] ; Wang, ZY (Wang, Zhanyong)[ 1 ]

JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS

卷: 45

期: 4

页: 1126-1132

DOI: 10.1016/j.jtice.2013.12.004

出版年: JUL 2014

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摘要

Water-soluble polysaccharides were obtained from Gentiana scabra Bunge. Response surface methodology was used to optimize the extraction conditions, and a central composite design was adopted to determine the optimal processing parameters. The optimum extraction conditions are as follows: extraction temperature, 100 degrees C; ratio of water to raw material, 26.56; extraction time, 3 h; and extraction frequency, 2. Under these conditions, the experimental yield of polysaccharides was 13.0 +/- 0.25%, which was consistent with the predicted yield. In vitro evaluation of the antioxidant activity suggests that the polysaccharides have high scavenging activity to 1,1-dipheny1-2-picrylhydrazyl radicals, relatively lower reducing power and scavenging activity to superoxide anions and hydroxyls. The polysaccharides also show high anti-tumor activity in vivo. (C) 2013 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
关键词

作者关键词olysaccharides; Response surface methodology; Gentiana scabra Bunge; Antioxidant; Anti-tumor

KeyWords Plus:RESPONSE-SURFACE METHODOLOGY; CRUDE POLYSACCHARIDES; IMMUNOMODULATORY ACTIVITY
作者信息

通讯作者地址: Wang, ZY (通讯作者)
[显示增强组织信息的名称]         Liaoning Shihua Univ, Coll Chem Chem Engn & Environm Engn, Fushun 113001, Peoples R China.

地址:
[显示增强组织信息的名称]         [ 1 ] Liaoning Shihua Univ, Coll Chem Chem Engn & Environm Engn, Fushun 113001, Peoples R China
              [ 2 ] Jilin Agr Univ, Sch Life Sci, Changchun 130118, Peoples R China

电子邮件地址:wangzy125@gmail.com
基金资助致谢
基金资助机构        授权号
Science Technology Foundation of Fushun city        
FSKJHT201135
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出版商

ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
类别 / 分类

研究方向:Engineering

Web of Science 类别:Engineering, Chemical
文献信息

文献类型:Article

语种:English

入藏号: WOS:000340352000004

ISSN: 1876-1070

电子 ISSN: 1876-1089
期刊信息

    目录: Current Contents Connect®

    Impact Factor (影响因子): Journal Citation Reports®

其他信息

IDS 号: AN1OA

Web of Science 核心合集中的 "引用的参考文献": 25

Web of Science 核心合集中的 "被引频次": 0
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3楼2014-09-23 19:22:49
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muse

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dennistt: 金币+10 2014-09-23 19:25:27
jssxh: 金币+10, LS-EPI+1, 谢谢参与,请继续关注本版块! 2014-09-24 08:38:26
入藏号: WOS:000340352000004
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