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| Ming-Xia Song, Chang-Ji Zheng, Xian-Qing Deng, Qing Wang, Shao-Pu Hou, Ting-Ting Liu, Xiao-Lan Xing, Hu-Ri Piao*. Synthesis and bioactivity evaluation of rhodanine derivatives as potential anti-bacterial agents. Eur J Med Chem. 2012. 54: 403-12. |
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±»ÒýƵ´Î: 8 1. Novel arylhydrazone derivatives bearing a rhodanine moiety: synthesis and evaluation of their antibacterial activities ×÷Õß: Li, Wei; Zheng, Chang-Ji; Sun, Liang-Peng; µÈ. ARCHIVES OF PHARMACAL RESEARCH ¾í: 37 ÆÚ: 7 Ò³: 852-861 ³ö°æÄê: JUL 2014 ³ö°æÉÌ´¦µÄÈ«ÎÄ ²é¿´ÕªÒª ±»ÒýƵ´Î: 0 (À´×Ô Web of Science µÄºËÐĺϼ¯) 2. Synthesis and evaluation of the antimicrobial activities of 3-((5-phenyl-1,3,4-oxadiazol-2-yl)methyl)-2-thioxothiazolidin-4-one derivatives ×÷Õß: Liu, Jia-Chun; Zheng, Chang-Ji; Wang, Meng-Xiao; µÈ. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ¾í: 74 Ò³: 405-410 ³ö°æÄê: MAR 3 2014 ³ö°æÉÌ´¦µÄÈ«ÎÄ ²é¿´ÕªÒª ±»ÒýƵ´Î: 1 (À´×Ô Web of Science µÄºËÐĺϼ¯) 3. Synthesis of 5-Benzylidine-3-alpha-carboxy Ethyl Rhodanines and Study of their Anticancer Activity Against HeLa Cell Lines and Antibacterial Activity Against MRSA ×÷Õß: Sundaram, Kaveri; Ravi, Subban ASIAN JOURNAL OF CHEMISTRY ¾í: 25 ÆÚ: 18 Ò³: 10353-10356 ×Ó¼: B ³ö°æÄê: DEC 2013 ²é¿´ÕªÒª ±»ÒýƵ´Î: 0 (À´×Ô Web of Science µÄºËÐĺϼ¯) 4. Synthesis and biological evaluation of rhodanine derivatives bearing a quinoline moiety as potent antimicrobial agents ×÷Õß: Guo, Meng; Zheng, Chang-Ji; Song, Ming-Xia; µÈ. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS ¾í: 23 ÆÚ: 15 Ò³: 4358-4361 ³ö°æÄê: AUG 1 2013 ³ö°æÉÌ´¦µÄÈ«ÎÄ ²é¿´ÕªÒª ±»ÒýƵ´Î: 3 (À´×Ô Web of Science µÄºËÐĺϼ¯) 5. Synthesis and biological evaluation of a new class of 4-aminoquinoline-rhodanine hybrid as potent anti-infective agents ×÷Õß: Chauhan, Kuldeep; Sharma, Moni; Saxena, Juhi; µÈ. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ¾í: 62 Ò³: 693-704 ³ö°æÄê: APR 2013 ³ö°æÉÌ´¦µÄÈ«ÎÄ ²é¿´ÕªÒª ±»ÒýƵ´Î: 11 (À´×Ô Web of Science µÄºËÐĺϼ¯) 6. A Simple and Green Procedure for the Synthesis of 5-Arylidenerhodanines Catalyzed by Diammonium Hydrogen Phosphate in Water ×÷Õß: Han, Liangliang; Wu, Tao; Zhou, Zhongqiang SCIENTIFIC WORLD JOURNAL ÎÄÏ׺Å: 543768 ³ö°æÄê: 2013 ³ö°æÉÌ´¦µÄÈ«ÎÄ ²é¿´ÕªÒª ±»ÒýƵ´Î: 0 (À´×Ô Web of Science µÄºËÐĺϼ¯) 7. Synthesis and biological evaluation of 5-aryloxypyrazole derivatives bearing a rhodanine-3-aromatic acid as potential antimicrobial agents ×÷Õß: Zheng, Chang-Ji; Song, Ming-Xia; Sun, Liang-Peng; µÈ. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS ¾í: 22 ÆÚ: 23 Ò³: 7024-7028 ³ö°æÄê: DEC 1 2012 ³ö°æÉÌ´¦µÄÈ«ÎÄ ²é¿´ÕªÒª ±»ÒýƵ´Î: 2 (À´×Ô Web of Science µÄºËÐĺϼ¯) 8. Discovery of a new class of dithiocarbamates and rhodanine scaffolds as potent antifungal agents: synthesis, biology and molecular docking ×÷Õß: Chauhan, Kuldeep; Sharma, Moni; Singh, Pratiksha; µÈ. MEDCHEMCOMM ¾í: 3 ÆÚ: 9 Ò³: 1104-1110 ³ö°æÄê: SEP 2012 ³ö°æÉÌ´¦µÄÈ«ÎÄ ²é¿´ÕªÒª |
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dengxianqing: ½ð±Ò+2, ¡ï¡ï¡ïºÜÓаïÖú 2014-09-20 13:18:35
dengxianqing: ½ð±Ò+2, ¡ï¡ï¡ïºÜÓаïÖú 2014-09-20 13:18:35
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Synthesis and bioactivity evaluation of rhodanine derivatives as potential anti-bacterial agents ×÷Õß:Song, MX (Song, Ming-Xia)[ 1 ] ; Zheng, CJ (Zheng, Chang-Ji)[ 1 ] ; Deng, XQ (Deng, Xian-Qing)[ 1 ] ; Wang, Q (Wang, Qing)[ 1 ] ; Hou, SP (Hou, Shao-Pu)[ 1 ] ; Liu, TT (Liu, Ting-Ting)[ 1 ] ; Xing, XL (Xing, Xiao-Lan)[ 1 ] ; Piao, HR (Piao, Hu-Ri)[ 1 ] EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY ¾í: 54 Ò³: 403-412 DOI: 10.1016/j.ejmech.2012.05.023 ³ö°æÄê: AUG 2012 ²é¿´ÆÚ¿¯ÐÅÏ¢ ÕªÒª Five series of (Z)-5-(4-(2-oxo-2-phenylethoxy)benzylidene)-2-thioxothiazolidin-4-one derivatives (I-V) were synthesized, characterized, and evaluated for their anti-bacterial activity. Most of the synthesized compounds showed potent inhibition against several Gram-positive bacteria (including multidrug-resistant clinical isolates) with MIC values in the range of 1-32 mu g/mL. Compounds IIIi, Vb and Vc presented the most potent activity, showing four-fold more potency than norfloxacin (MIC = 8 mu g/mL and 4 mu g/mL) and 64-fold more activity than oxacillin (MIC > 64 mu g/mL) against MRSA CCARM 3167 and 3506 strains with MIC values of 1 mu g/mL, and 64-fold more potency than norfloxacin (MIC > 64 mu g/mL) and comparable activity to oxacillin (MIC = 1 mu g/mL) against the QRSA CCARM 3505 and 3519 strains. None of the compounds exhibited any activity against the Gram-negative bacteria Escherichia coli 1356 at 64 mu g/mL. (C) 2012 Elsevier Masson SAS. All rights reserved. ¹Ø¼ü´Ê ×÷Õ߹ؼü´Ê:Rhodanine; Propanoic acid; Acetic acid; Anti-bacterial activity KeyWords Plus:ANTIFUNGAL; INHIBITORS; 4-THIAZOLIDINONE; ACID ×÷ÕßÐÅÏ¢ ͨѶ×÷ÕßµØÖ·: Piao, HR (ͨѶ×÷Õß) Yanbian Univ, Coll Pharm, Affiliated Minist Educ, Key Lab Nat Resources & Funct Mol Changbai Mt, Yanji 133002, Jilin Province, Peoples R China. µØÖ·: [ 1 ] Yanbian Univ, Coll Pharm, Affiliated Minist Educ, Key Lab Nat Resources & Funct Mol Changbai Mt, Yanji 133002, Jilin Province, Peoples R China µç×ÓÓʼþµØÖ·:piaohuri@yahoo.com.cn »ù½ð×ÊÖúÖÂл »ù½ð×ÊÖú»ú¹¹ ÊÚȨºÅ National Science Foundation of China 20962021 ²é¿´»ù½ð×ÊÖúÐÅÏ¢ ³ö°æÉÌ ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 23 RUE LINOIS, 75724 PARIS, FRANCE Àà±ð / ·ÖÀà Ñо¿·½Ïò harmacology & PharmacyWeb of Science Àà±ð:Chemistry, Medicinal ÎÄÏ×ÐÅÏ¢ ÎÄÏ×ÀàÐÍ:Article ÓïÖÖ:English Èë²ØºÅ: WOS:000307920600042 ISSN: 0223-5234 ÆÚ¿¯ÐÅÏ¢ Impact Factor (Ó°ÏìÒò×Ó): Journal Citation Reports® ÆäËûÐÅÏ¢ IDS ºÅ: 994HD Web of Science ºËÐĺϼ¯ÖÐµÄ "ÒýÓõIJο¼ÎÄÏ×": 18 Web of Science ºËÐĺϼ¯ÖÐµÄ "±»ÒýƵ´Î": 8 »¯ºÏÎï 1 ÖÁ 10 1. »¯ºÏÎïÏêϸÐÅÏ¢ 2. »¯ºÏÎïÏêϸÐÅÏ¢ 3. »¯ºÏÎïÏêϸÐÅÏ¢ 4. »¯ºÏÎïÏêϸÐÅÏ¢ 5. »¯ºÏÎïÏêϸÐÅÏ¢ 6. »¯ºÏÎïÏêϸÐÅÏ¢ 7. »¯ºÏÎïÏêϸÐÅÏ¢ 8. »¯ºÏÎïÏêϸÐÅÏ¢ 9. »¯ºÏÎïÏêϸÐÅÏ¢ 10. »¯ºÏÎïÏêϸÐÅÏ¢ |
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5Â¥2014-09-20 13:18:17
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