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【答案】应助回帖
★ ★ ★ ★ ★
感谢参与，应助指数 +1
大胜520莹莹: 金币+5, ★★★★★最佳答案 2014-09-22 18:46:12
oven1986: LS-EPI+1, 感谢应助！ 2014-09-22 19:31:15
这篇文章被检索了， 下次写文章标题时注意下拼写，你的文题的第一个单词貌似拼错了，下次可以顺便把DOI之类的都给出来，这样更方便检索
Hypolipidaemic and antioxidant properties of ethanol extract from Flos populi
作者:Zhao, Y (Zhao, Yan)[ 1 ] ; Tang, GS (Tang, Guosheng)[ 1 ] ; Cai, EB (Cai, Enbo)[ 1 ] ; Liu, SL (Liu, Shuangli)[ 1 ] ; Zhang, LX (Zhang, Lianxue)[ 1 ] ; Wang, SJ (Wang, Shijie)[ 2 ]
NATURAL PRODUCT RESEARCH
卷: 28 期: 18 页: 1467-1470
DOI: 10.1080/14786419.2014.905564
出版年: 2014
查看期刊信息
摘要
This study was undertaken to evaluate antihyperlipidaemic and in vitro antioxidant activity of ethanolic extract of Flos populi (EFP). The results demonstrated that EFP contains 78.5% flavonoids and 10.4% phenolics, and it exhibited free radical-scavenging activity on 2,2-diphenyl-picrylhydrazyl (IC50 36.40 +/- 0.62 mu g/mL) and high reducing power (EC50 206.32 +/- 1.6 mu g/mL) under in vitro chemical assays. And irrespective of prophylactic administration or remedial administration, in high fat diet-induced hyperlipidaemic mice, oral treatment with EFP produced a decrease in the levels of serum total cholesterol, triglycerides, low-density lipoprotein-cholesterol and increase in high-density lipoprotein-cholesterol. In a word, in high fat diet-fed hyperlipidaemic mice, EFP (100, 200 and 400 mg/kg) significantly altered the plasma lipid levels to near normal. These results support a potential effect of EFP in cardiovascular disease.
关键词
作者关键词:Flos populi; flavonoids; phenols; antioxidant; hypolipidaemic
作者信息
通讯作者地址: Zhang, LX (通讯作者)
Jilin Agr Univ, Coll Chinese Med Mat, Changchun 130118, Jilin, Peoples R China.
地址:
[ 1 ] Jilin Agr Univ, Coll Chinese Med Mat, Changchun 130118, Jilin, Peoples R China
[ 2 ] Jilin Agr Sci & Technol Univ, Coll Tradit Chinese Med, Changchun, Jilin, Peoples R China
电子邮件地址:zlx863@163.com
基金资助致谢
基金资助机构 授权号
Nature Science Foundation of China
31000154
National Science and Technology Support Program of China
2011BAI03B01
National Nonprofit Industry Research Special Program of China
201303111
Jilin Province Science and Technology Development Program
20126046
20140204013YY
Special Program in the Pharmaceutical Industry in Jilin Province
YYZX201258
查看基金资助信息
出版商
TAYLOR & FRANCIS LTD, 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND
类别 / 分类
研究方向:Chemistry; Pharmacology & Pharmacy
Web of Science 类别:Chemistry, Applied; Chemistry, Medicinal
文献信息
文献类型:Article
语种:English
入藏号: WOS:000340273000007
ISSN: 1478-6419
电子 ISSN: 1478-6427
期刊信息
Impact Factor (影响因子): Journal Citation Reports®
其他信息
IDS 号: AN0KH
Web of Science 核心合集中的 "引用的参考文献": 6
Web of Science 核心合集中的 "被引频次": 0 |
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