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南方医科大学南方医院张镇海团队现向国内外公开招聘生物学博士后或技术员1-2名
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南方医科大学南方医院张镇海团队，现向国内外公开招聘生物学博士后研究人员一名： 具有分子生物学、细胞生物学、和生物化学等学科研究背景，以有过免疫学研究经历优先。以第一作者发表过SCI论文，工作勤奋。 研究方向：利用免疫学以及生物信息学方法克隆与抗原特异性结合的高亲和性的抗体。 本实验室主要研究方向为：HIV-1广谱抗体筛选、IgA肾炎等自免疫疾病的致病、进展机制及预防。 有意者请email联系： zhenhai@smu.edu.cn 11920118@qq.com 前期发表文章： Zhang Z, Wippo CJ, Wal M, Ward E, Korber P, and Pugh BF. A packing mechanism for nucleosome organization reconstituted across a eukaryotic genome. Science. 2011 May 20;332(6032):977-80. [IF: 31.027] Reported by PennState Science (http://science.psu.edu/news-and-events/2011-news/Pugh5-2011) 2. Zhang Z and Pugh BF. High-Resolution Genome-wide Mapping of the Primary Structure of Chromatin. Cell. 2011 Jan 21;144(2):175-86. [IF: 31.957] 3. Zhang Z and Pugh BF. Genomic organization of H2Av containing nucleosomes in Drosophila heterochromatin. PLoS ONE. 2011;6(6):e20511. Epub 2011 Jun 27. FlyBase ID: FBrf0214284. [IF: 3.73] 4. Wu T, Zhang Z, Yuan Z, Lo LJ, Chen J, Wang Y, Peng J. Distinctive Genes Determine Different Intramuscular Fat and Muscle Fiber Ratios of the longissimus dorsi Muscles in Jinhua and Landrace Pigs. PLoS One. 2013;8(1):e53181. [IF: 3.73] 5. Lo L, Zhang Z, Hong N, Peng J, Hong Y. 3640 unique EST clusters from the medaka testis and their potential use for identifying conserved testicular gene expression in fish and mammals. PLoS ONE. 2008;3(12):e3915. [IF: 3.73] 6. Cheng W, Guo L, Zhang Z, Soo HM, Wen C, Wu W, Peng J. HNF factors form a network to regulate liver-enriched genes in zebrafish. Dev Biol. 2006 Jun 15;294(2):482-96. [IF: 4.064] 7. Wen C, Zhang Z, Ma W, Xu M, Wen Z, Peng J. Genome-wide identification of female-enriched genes in zebrafish. Dev Dyn. 2005 Jan;232(1):171-9. [IF: 2.59] 8. Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, Dekosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, Druz A, Garrett NJ, Hoi KH, Kong R, Louder MK, Longo NS, McKee K, Nonyane M, O'Dell S, Roark RS, Rudicell RS, Schmidt SD, Sheward DJ, Soto C, Wibmer CK, Yang Y, Zhang Z, Nisc Comparative Sequencing, Mullikin JC, Binley JM, Sanders RW, Wilson IA, Moore JP, Ward AB, Georgiou G, Williamson C, Abdool Karim SS, Morris L, Kwong PD, Shapiro L, Mascola JR. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 2014 Mar 2. doi: 10.1038/nature13036. [Epub ahead of print] [IF: 38.597] 9. Sundling C, Zhang Z, Phad GE, Sheng Z, Wang Y, John, Mascola R, Li Y, Wyatt RT, Shapiro L, Karlsson Hedestam GB. Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse immunoglobulin repertoire following immunization. J Immunol. 2014 Mar 12. [Epub ahead of print] [IF: 5.076] 10. Zhou T, Zhu J, Wu X, Moquin S, Zhang B, Acharya P, Georgiev IS, Altae-Tran HR, Chuang GY, Joyce MG, Do Kwon Y, Longo NS, Louder MK, Luongo T, McKee K, Schramm CA, Skinner J, Yang Y, Yang Z, Zhang Z, Zheng A, Bonsignori M, Haynes BF, Scheid JF, Nussenzweig MC, Simek M, Burton DR, Koff WC; NISC Comparative Sequencing Program, Mullikin JC, Connors M, Shapiro L, Nabel GJ, Mascola JR, Kwong PD. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity. 2013 S1074-7613(13)00297-5 (Eput ahead of print) [IF: 19.795] 11. Chintapalli SV, Bhardwaj G, Babu J, Hadjiyianni L, Hong Y, Todd GK, Boosalis CA, Zhang Z, Zhou X, Ma H, Anishkin A, van Rossum DB, Patterson RL. Reevaluation of the evolutionary events within recA/RAD51 phylogeny. BMC Genomics. 2013 Apr 10;14(1):240. doi: 10.1186/1471-2164-14-240. [IF: 4.397] 12. Liao HX, Lynch R, Zhou T, Gao F, Alam SM, Boyd SD, Fire AZ, Roskin KM, Schramm CA, Zhang Z, Zhu J, Shapiro L; NISC Comparative Sequencing Program, Mullikin JC, Gnanakaran S, Hraber P, Wiehe K, Kelsoe G, Yang G, Xia SM, Montefiori DC, Parks R, Lloyd KE, Scearce RM, Soderberg KA, Cohen M, Kamanga G, Louder MK, Tran LM, Chen Y, Cai F, Chen S, Moquin S, Du X, Joyce MG, Srivatsan S, Zhang B, Zheng A, Shaw GM, Hahn BH, Kepler TB, Korber BT, Kwong PD, Mascola JR, Haynes BF. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature. 2013 Apr 25;496(7446):469-76. [IF: 38.597] 13. Zhu J, Ofek G, Yang Y, Zhang B, Louder MK, Lu G, McKee K, Pancera M, Skinner J, Zhang Z, Parks R, Eudailey J, Lloyd KE, Blinn J, Alam SM, Haynes BF, Simek M, Burton DR, Koff WC; NISC Comparative Sequencing Program, Mullikin JC, Mascola JR, Shapiro L, Kwong PD. Mining the antibodyomes for HIV-1-neutralizing antibodies with next-generation sequencing and phylogenetic pairing of heavy/light chains. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6470-5. [IF: 9.737] 14. Zhu J, O'Dell S, Ofek G, Pancera M, Wu X, Zhang B, Zhang Z; NISC Comparative Sequencing Program, Mullikin JC, Simek M, Burton DR, Koff WC, Shapiro L, Mascola JR, Kwong PD. Somatic populations of PGT135-137 HIV-1-neutralizing antibodies identified by 454 pyrosequencing and bioinformatics. Frontiers in Microbiology. 2012 doi: 10.3389/fmicb.2012.00315. [New Journal, no IF] 15. Bhardwaj G, Ko KD, Hong Y, Zhang Z, Ho NL, Chintapalli SV, Kline LA, Gotlin M, Hartranft DN, Patterson ME, Dave F, Smith EJ, Holmes EC, Patterson RL, van Rossum DB. PHYRN: a robust method for phylogenetic analysis of highly divergent sequences. PLoS One. 2012;7(4):e34261. Epub 2012 Apr 13. [IF: 3.73] 16. Batta K, Zhang Z, Yen K, Goffman DB, and Pugh BF. Genome-wide function of H2B ubiquitylation in promoter and genic regions. Genes Dev. 2011 Nov 1;25(21):2254-65. [IF: 12.444] 17. Wu X, Zhou T, Zhu J, Zhang B, Georgiev I, Wang C, Chen X, Longo NS, Louder M, McKee K, O'Dell S, Perfetto S, Schmidt SD, Shi W, Wu L, Yang Y, Yang ZY, Yang Z, Zhang Z, Bonsignori M, Crump JA, Kapiga SH, Sam NE, Haynes BF, Simek M, Burton DR, Koff WC, Doria-Rose NA, Connors M; NISC Comparative Sequencing Program, Mullikin JC, Nabel GJ, Roederer M, Shapiro L, Kwong PD, Mascola JR. Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Crystal Structures and Deep Sequencing. Science. 2011 Sep 16;333(6049):1593-602. Epub 2011 Aug 11. (Cover story) [IF: 31.027] 18. Schuster SC, Miller W, Ratan A, Tomsho LP, Giardine B, Kasson LR, Harris RS, Petersen DC, Zhao F, Qi J, Alkan C, Kidd JM, Sun Y, Drautz DI, Bouffard P, Muzny DM, Reid JG, Nazareth LV, Wang Q, Burhans R, Riemer C, Wittekindt NE, Moorjani P, Tindall EA, Danko CG, Teo WS, Buboltz AM, Zhang Z, Ma Q, Oosthuysen A, Steenkamp AW, Oostuisen H, Venter P, Gajewski J, Zhang Y, Pugh BF, Makova KD, Nekrutenko A, Mardis ER, Patterson N, Pringle TH, Chiaromonte F, Mullikin JC, Eichler EE, Hardison RC, Gibbs RA, Harkins TT, Hayes VM. Complete Khoisan and Bantu genomes from southern Africa. Nature 2010 Feb 18;463(7283):943-7. [IF: 38.597] 19. Hong Y, Chintapalli SV, Ko KD, Bhardwaj G, Zhang Z, van Rossum D, Patterson RL. Predicting Protein Folds with Fold-Specific PSSM Libraries. PLoS One. 2011;6(6):e20557. Epub 2011 Jun 16. [IF: 3.73] 20. Chen J, Ng SM, Chang C, Zhang Z, Bourdon JC, Lane DP, Peng J. p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish. Genes Dev. 2009 Feb 1;23(3):278-90. [IF: 12.444] 21. ChenJ,RuanH,NgSM,GaoC,SooHM,WuW,ZhangZ,WenZ,LaneDP,PengJ.Lossof function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish. Genes Dev. 2005 Dec 1;19(23):2900-11. [IF: 12.444] |
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