| 查看: 1391 | 回复: 9 | |||
| 当前只显示满足指定条件的回帖，点击这里查看本话题的所有回帖 | |||
zhenyuhao金虫 (小有名气)
|
[求助]
急，跪求英语单词解释
|
||
|
Cytospolides， Nonanolides， |
回复此楼» 猜你喜欢
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有6人回复
-
售一区SCI文章T0P，我:8O.551.O54,科目全,可十急
已经有9人回复
-
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有3人回复
-
考博求助
已经有3人回复
-
售SCI一区文章，我:8.O.551.O.5.4,科目全,可伽急
已经有5人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.5.4,科目全,可+急
已经有4人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.5.4,科目全,可+急
已经有5人回复
-
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有9人回复
-
售一区SCI文章T0P，我:8O.551.O54,科目全,可十急
已经有9人回复
-
售SCI一区T0P文章，我:8.O.55.1.O.5.4,科目全,可+急
已经有10人回复
xux730
铁杆木虫 (著名写手)
- 翻译EPI: 86
- 应助: 1719 (讲师)
- 金币: 10740.4
- 散金: 50
- 红花: 43
- 帖子: 2947
- 在线: 336.5小时
- 虫号: 1374299
- 注册: 2011-08-20
- 专业: 细胞周期与调控
【答案】应助回帖
★
RXMCDM: 金币+1, 多谢应助！ 2014-08-04 17:06:24
RXMCDM: 金币+1, 多谢应助！ 2014-08-04 17:06:24
|
这应该是原文，请邮寄合成的高手一试。 Cytospolides A–E (1–5), five new nonanolides with an unprecedented 15-carbon skeleton with the unique chemical feature of a C-2 methyl group, were isolated from the endophytic fungus Cytospora sp. The structures were elucidated by spectroscopic analysis, chemical interconversion, and single-crystal XRD. The solution and solid state conformers were compared by experimental methods (X-ray, NMR) and solvent and gas phase DFT calculations. The absolute configurations were assigned by time dependent (TD)-DFT calculations of CD spectra, including solution and solid state CD/TD-DFT approaches. The cytotoxicity assay of C-2 epimers showed significantly different activity against A549, suggesting that the C-2 methyl group has an important role in growth inhibition towards the tumor line. The existence of two conformers of the bioactive epimer in solution was proven by the soft pulse transfer NMR technique and further supported by DFT calculations. The discovery of the new metabolites not only extends the nonanolide family with cytospolide-type skeletons but also gives insight into the biosynthetic process of these fungal metabolites. |
7楼2014-08-03 22:58:09
Jonesupermax
金虫 (正式写手)
- 翻译EPI: 1
- 应助: 9 (幼儿园)
- 金币: 2168.1
- 散金: 130
- 帖子: 615
- 在线: 128.4小时
- 虫号: 1438918
- 注册: 2011-10-12
- 性别: GG
- 专业: 有机合成
2楼2014-08-03 10:20:54
Jonesupermax
金虫 (正式写手)
- 翻译EPI: 1
- 应助: 9 (幼儿园)
- 金币: 2168.1
- 散金: 130
- 帖子: 615
- 在线: 128.4小时
- 虫号: 1438918
- 注册: 2011-10-12
- 性别: GG
- 专业: 有机合成
3楼2014-08-03 10:28:09
zhenyuhao
金虫 (小有名气)
- 应助: 0 (幼儿园)
- 金币: 843.8
- 散金: 31
- 帖子: 143
- 在线: 43小时
- 虫号: 1226648
- 注册: 2011-03-09
- 性别: GG
- 专业: 生物物理、生物化学与分子
4楼2014-08-03 11:17:36
