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uptake clearance
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zhanglu207
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- Ó¦Öú: 1 (Ó×¶ùÔ°)
- ½ð±Ò: 166.2
- É¢½ð: 2
- Ìû×Ó: 90
- ÔÚÏß: 53.5Сʱ
- ³æºÅ: 1760655
- ×¢²á: 2012-04-17
- רҵ: »ù´¡ÊÞҽѧ
2Â¥2014-07-02 16:10:52
Ekoay
½ð³æ (³õÈëÎÄ̳)
- Ó¦Öú: 0 (Ó×¶ùÔ°)
- ½ð±Ò: 370.3
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- ³æºÅ: 2745776
- ×¢²á: 2013-10-22
- ÐÔ±ð: MM
- רҵ: Ò©Îï·ÖÎö

3Â¥2014-07-03 11:32:17
Ekoay
½ð³æ (³õÈëÎÄ̳)
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- ³æºÅ: 2745776
- ×¢²á: 2013-10-22
- ÐÔ±ð: MM
- רҵ: Ò©Îï·ÖÎö
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Differences in the expression and function of the organic anion transporting polypeptide (OATP) transporters contribute to inter-individual variability in atorvastatin clearance. However, the importance of the bile acid transporter NTCP (SLC10A1) in atorvastatin uptake clearance (CLupt) is not yet clarified. To elucidate this issue, weinvestigated the relative contribution of NTCP, OATP1B1, OATP1B3, and OATP2B1 to atorvastatin CLupt in twelve human liver samplesÕâÒ»¶ÎÊÇÕªÒªµÄÒ»²¿·Ö£¬ÎÄÕÂÌâÄ¿ÊÇ£ºHepatic uptake of atorvastatin: influence of variability in transporter expression on uptake clearance and drug-drug interactions |

4Â¥2014-07-03 11:36:17














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