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jiangyumin2
铁杆木虫 (著名写手)
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4楼2014-05-14 15:10:13
baiyuefei
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2楼2014-05-14 14:52:20
baiyuefei
版主 (文学泰斗)
风雪
- LS-EPI: 1647
- 应助: 4643 (副教授)
- 贵宾: 46.97
- 金币: 659352
- 散金: 11616
- 红花: 995
- 沙发: 81
- 帖子: 69618
- 在线: 13523.9小时
- 虫号: 676696
- 注册: 2008-12-18
- 性别: GG
- 专业: 合成药物化学
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abrication and cyto-compatibility of Fe3O4/SiO2/graphene-CdTe QDs/CS nanocomposites for drug delivery. 作者:Ou, Jun; Wang, Fang; Huang, Yuanjie; Li, Duosheng; Jiang, Yuming; Qin, Qing-Hua; Stachurski, Z H; Tricoli, Antonio; Zhang, Tina Colloids and surfaces. B, Biointerfaces 卷:117 页:466-72 DOI:10.1016/j.colsurfb.2013.12.003 出版年:2014-May-1 (Epub 2013 Dec 11) 摘要 Synthesis of magnetic Fe3O4/SiO2/graphene-CdTe QDs/chitosan nanocomposites (FGQCs) is investigated with respect to their potential of improving the drug loading content above that of magnetic/fluorescent bifunctional nanocomposites. To evaluate the performance of the FGQCs, their surface morphology was thoroughly assessed. The in vitro interaction between the FGQCs and heptoma cell line smmc-7721 cells was observed for the first time by TEM ultrathin section imaging. At an excitation wavelength of 365nm, the graphene-QDs exhibit a strong luminescence in aqueous environments. The loading content and entrapment efficiency of the FGQCs were 70% and 50%, respectively. The cytotoxicity of this novel drug delivery system was evaluated in vitro using heptoma cell line smmc-7721 and quantified by the 3-(4,5-dimethylthiazol-z-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The results show that FGQCs are a promising new multifunctional material for drug delivery in biological and medical applications. Copyright 2013 Elsevier B.V. All rights reserved. 关键词 关键词列表:CdTe QDs; Drug delivery; Graphene cytotocity; Luminescence; Multifunctional 作者信息 地址:Materials Science and Engineering College, Guilin University of Technology, Guilin 541004, China; Ministry-Province Jointly-Constructed Cultivation Base for State Key Laboratory of Processing for Non-ferrous Metal and Featured Materials, Guangxi Zhuang Autonomous Region, Guilin, China. Electronic address: gloujun123@gmail.com. 文献信息 文献类型:Journal Article 语种:English PubMed ID:24373978 NLM 唯一 ID:9315133 创建日期: 30 Apr 2014 电子出版:11 Dec 2013 国家/地区: Netherlands ISSN:1873-4367 其他信息 |
3楼2014-05-14 14:52:36
jiangyumin2
铁杆木虫 (著名写手)
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- 性别: GG
- 专业: 功能与智能高分子
5楼2014-05-14 15:11:56