24小时热门版块排行榜    

查看: 287  |  回复: 1

cainiaodui

新虫 (小有名气)

[求助] 翻译求助

This is paradoxical, however. One would expect that destroying the vasculature would severely compromise the delivery of oxygen
and therapeutics to the solid tumor, producing hypoxia that would render many chemotherapeutics, as well as radiation, less effective.Indeed, some studies show that antiangiogenic therapy can compromise the delivery of drugs to tumors, as well as antagonize the outcome of radiation therapy . How can we reconcile these diametrically opposed outcomes of combination therapy with the positive preclinical and clinical data? The answer to this question is critical for optimizing the efficacy of combined antiangiogenic and cytotoxic therapy.
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

reko34

木虫 (正式写手)

【答案】应助回帖

★ ★ ★ ★ ★ ★
RXMCDM: 金币+1 2014-05-12 12:14:21
cainiaodui(RXMCDM代发): 金币+5 2014-06-09 07:37:20
然而这是矛盾的。人们推断,破坏血管会在氧气供应和针对实体肿瘤的治疗之间折中,产生缺氧,使很多化疗以及放射效果减弱。的确,一些研究表示,抗血管生成疗法会减弱药物至肿瘤的传递,也会减弱放疗的效果。我们该如何用正面的临床前和临床数据去协调这些截然相反的联合治疗结论?答案对改进联合抗血管生成疗法和细胞毒药物疗法的效果是关键的。
2楼2014-05-12 12:01:22
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 cainiaodui 的主题更新
信息提示
请填处理意见