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cainiaodui新虫 (小有名气)
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| Researchers have half-jokingly dubbed this phenomenon “vessel abnormalization,” a reference to the vessel normalization hypothesis of Harvard cancer researcher Rakesh Jain, Ph.D. His theory holds that VEGF blockers shrink tumors by normalizing some nonfunctional blood vessels near the tumor, allowing chemotherapy drugs to better reach their target. For DLL4, researchers are hoping that the opposite is true: that anti-DLL4 drugs will unleash a burst of abnormal blood vessel growth around the tumor, starving it of oxygen, and perhaps making chemotherapy drugs even more effective by presenting them a target rich in dividing cells. |
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reko34
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