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347416682金虫 (小有名气)
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[求助]
求助中文摘要翻译成英文。。。 已有3人参与
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347416682
金虫 (小有名气)
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12楼2014-05-24 15:09:55
环保小卫士
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2楼2014-04-27 23:48:58
环保小卫士
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★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ...
347416682(greenhand_ku代发): 金币+30, 感谢您的热心帮助,欢迎常来本版交流指导! 2014-05-01 09:45:45
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347416682: 金币+20, ★★★很有帮助 2014-05-20 10:47:28
347416682(greenhand_ku代发): 金币+30, 感谢您的热心帮助,欢迎常来本版交流指导! 2014-05-01 09:45:45
347416682: 金币+20, ★★★很有帮助, 多谢啦 2014-05-20 10:46:46
347416682: 金币+20, ★★★很有帮助 2014-05-20 10:47:28
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In the late 1960s,Cisplatin was found has curative effect to a variety of cancers.Soon afters,plenty of Platinum derivatives were synthesized constantly.However,it's necessary to exploit new kinds of cisplatin anti-cancer drug because of its strong toxic and side effects.Steroids is a type of native compound with physiological activity,which is widely existed in creature having biological activity to various cancer cells.If combine sterides with metal effect groups,it may create a better result of suppressing tumor growth. Based on researches on steroidal compounds against tumor and metal complexes may have antitumor activity previously.This paper designed synthesis 23 new steroidal metal complexes and test biological activity on some of them.Four 3 - any thiourea steroidal metal complexes,nine 20 - ammonia thiourea steroidal metal complexes and ten 17 - ammonia thiourea steroidal metal complexes included and measure some compouds on antitumor activity in vitro. 楼主这是前两段,请查收! |

3楼2014-04-30 21:17:19
环保小卫士
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347416682(greenhand_ku代发): 金币+30, 辛苦了,有空请常来本版交流! 2014-05-01 09:47:04
greenhand_ku: 应助指数+1, 谢谢积极应助 2014-05-21 09:18:34
greenhand_ku: SFL-EPI+1, 鼓励较大篇幅的手工翻译应助 2014-05-21 09:25:20
347416682(greenhand_ku代发): 金币+30, 辛苦了,有空请常来本版交流! 2014-05-01 09:47:04
greenhand_ku: 应助指数+1, 谢谢积极应助 2014-05-21 09:18:34
greenhand_ku: SFL-EPI+1, 鼓励较大篇幅的手工翻译应助 2014-05-21 09:25:20
|
1.Synthesising 20 - ammonia thiourea steroidal metal complexes.Puting changed pregnenolone third-substituent react with thiosemicarbazone with different substituents.And then,reacting with K2PtCl4,CuCl2·2H2O,[Ru(η6-p-cymene)Cl2]2,from which we can get 8 kinds of metallic 20 - ammonia thiourea class steroid complexes.Reacting oestrone with 2 - hydrazine base pyridine,then reacting with CuCl2·2H2O,gaining 20 - hydrazine (2 -) pyridine steroidal metal complexes.We can discover that some compounds show good activity of inhibiting tumor cell proliferation from antitumor activity in vitro experiment.Such as compoud 4 and compoud 9,their IC50 figure to HELA cell is 9.5μmol/L and 4.8μmol/L. 第三段 |

4楼2014-04-30 22:49:44










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