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Proc Natl Acad Sci U S A 谁知道这个是什么期刊
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如题。这个期刊是在NCBI上搜到的信息 Zhonghua Yi Xue Za Zhi. 2007 Nov 27;87(44):3152-4.Links [Expression profile of receptor-interacting protein 140 in the brain: experiment with prenatal and postnatal mice][Article in Chinese] Zhang XR, Zeng CM, DU JB, Liang R, Yang LJ, Yu WD, Guo JZ. Department of Pediatrics, People's Hospital, Peking University, Beijing 100044, China. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2907-12. Epub 2008 Feb 15. Links SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland.Fauquier T, Rizzoti K, Dattani M, Lovell-Badge R, Robinson IC. Division of Molecular Neuroendocrinology, Medical Research Council, National Institute of Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom. The pituitary gland adapts the proportion of each of its endocrine cell types to meet differing hormonal demands throughout life. There is circumstantial evidence that multipotent adult progenitor cells contribute to this plasticity, but these cells have not been identified. Here, we describe a small (<0.05%) population of progenitor cells in the adult pituitary gland. We show that these cells express SOX2, a marker of several early embryonic progenitor and stem cell types, and form "pituispheres" in culture, which can grow, form secondary spheres, and differentiate to all of the pituitary endocrine cell types, as well as folliculostellate cells. Differentiation of cells in the pituispheres was associated with the expression of nestin, SOX9, and S100. Cells expressing SOX2 and E-cadherin are found throughout Rathke's pouch (RP) in embryos but persist in the adult gland, mostly in a narrow zone lining the pituitary cleft, but also are scattered throughout the pituitary. However, unlike in embryonic RP, most of these SOX2(+) cells in the adult gland also express SOX9 and S100. We suggest that this SOX2(+)/SOX9(+) population represents transit-amplifying cells, whereas the SOX2(+)/SOX9(-) cells we identify are multipotent progenitor/stem cells persisting in the adult pituitary. 里面的。但是不知道这个期刊好不好。所以想了解一下。 |
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