| 查看: 1276 | 回复: 6 | |||
| 当前主题已经存档。 | |||
[交流]
Proc Natl Acad Sci U S A 谁知道这个是什么期刊
|
|||
|
如题。这个期刊是在NCBI上搜到的信息 Zhonghua Yi Xue Za Zhi. 2007 Nov 27;87(44):3152-4.Links [Expression profile of receptor-interacting protein 140 in the brain: experiment with prenatal and postnatal mice][Article in Chinese] Zhang XR, Zeng CM, DU JB, Liang R, Yang LJ, Yu WD, Guo JZ. Department of Pediatrics, People's Hospital, Peking University, Beijing 100044, China. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2907-12. Epub 2008 Feb 15. Links SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland.Fauquier T, Rizzoti K, Dattani M, Lovell-Badge R, Robinson IC. Division of Molecular Neuroendocrinology, Medical Research Council, National Institute of Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom. The pituitary gland adapts the proportion of each of its endocrine cell types to meet differing hormonal demands throughout life. There is circumstantial evidence that multipotent adult progenitor cells contribute to this plasticity, but these cells have not been identified. Here, we describe a small (<0.05%) population of progenitor cells in the adult pituitary gland. We show that these cells express SOX2, a marker of several early embryonic progenitor and stem cell types, and form "pituispheres" in culture, which can grow, form secondary spheres, and differentiate to all of the pituitary endocrine cell types, as well as folliculostellate cells. Differentiation of cells in the pituispheres was associated with the expression of nestin, SOX9, and S100. Cells expressing SOX2 and E-cadherin are found throughout Rathke's pouch (RP) in embryos but persist in the adult gland, mostly in a narrow zone lining the pituitary cleft, but also are scattered throughout the pituitary. However, unlike in embryonic RP, most of these SOX2(+) cells in the adult gland also express SOX9 and S100. We suggest that this SOX2(+)/SOX9(+) population represents transit-amplifying cells, whereas the SOX2(+)/SOX9(-) cells we identify are multipotent progenitor/stem cells persisting in the adult pituitary. 里面的。但是不知道这个期刊好不好。所以想了解一下。 |
回复此楼» 猜你喜欢
309求调剂
已经有8人回复
-
一志愿南航 335分 | 0856 | GPA 4.07 | 有科研经历
已经有8人回复
-
求调剂
已经有5人回复
-
求化学调剂
已经有5人回复
-
085600，材料与化工321分求调剂
已经有10人回复
-
0703 化学 求调剂，一志愿山东大学 342 分
已经有5人回复
-
一志愿南开大学0710生物学359求调剂
已经有3人回复
-
085600，专业课化工原理，320分求调剂
已经有4人回复
-
材料与化工272求调剂
已经有16人回复
-
290求调剂
已经有3人回复
克隆大虾
铁杆木虫 (著名写手)
- BioEPI: 1
- 应助: 133 (高中生)
- 金币: 6015.9
- 散金: 236
- 红花: 10
- 帖子: 2367
- 在线: 1337.3小时
- 虫号: 93868
- 注册: 2005-09-15
- 性别: GG
- 专业: 微生物生理与生物化学
2楼2008-03-04 23:02:41
游侠892
铁杆木虫 (著名写手)
- 应助: 49 (小学生)
- 金币: 8246.4
- 散金: 76
- 红花: 6
- 帖子: 2102
- 在线: 138.9小时
- 虫号: 490693
- 注册: 2008-01-03
- 专业: 作物种质资源与遗传育种学
3楼2008-03-05 14:10:51
elvias
铁杆木虫 (正式写手)
- 应助: 4 (幼儿园)
- 贵宾: 0.005
- 金币: 5850.5
- 红花: 7
- 帖子: 389
- 在线: 91.5小时
- 虫号: 302177
- 注册: 2006-12-02
- 性别: GG
- 专业: 肿瘤免疫
4楼2008-03-05 19:31:24
5楼2008-03-10 19:46:08
10