| 查看: 597 | 回复: 1 | |||
[交流]
Leonard R. MacGillivray已有1人参与
|
 http://www.chem.uiowa.edu/people/leonard-r-macgillivray  http://pubs.rsc.org/en/Content/A ... 51073E#!divAbstract Leonard R. MacGillivray Leonard R. MacGillivray Professor Phone: 319-335-3504 Office: E555 CB Email: len-macgillivray@uiowa.edu CV: View/Download File Group Homepage: http://www.chem.uiowa.edu/macgillivray-research-group Divisions: Organic Chemistry Biosketch: B.S., Saint Mary's University (1994) Ph.D., University of Missouri-Columbia (1998) Research Associate, Steacie Institute for Molecular Sciences, National Research Council of Canada (1998-2000) Adjunct Research Professor, Ottawa-Carleton Chemistry Institute (1999-2000) Keywords: Molecular recognition; solid state organic and inorganic chemistry; crystal photochemistry; nanotechnology. Synthesis of porous molecular solids and nanometer scale molecular structures for applications in separations, catalysis, and molecular switching. Organic solid state synthesis by design. Research Interests: Whereas more traditional approaches to chemical synthesis have focused upon atoms and molecules individually, our research encompasses understanding principles that govern the effects of intermolecular interactions (e.g. hydrogen bonds) on the structure and properties of assemblies of atoms and molecules in the field of supramolecular chemistry. The structure of DNA and ability of enzymes to catalyze chemical reactions are examples from biochemistry that are regulated by such interactions and we address whether such forces may be used to confront long-standing problems with new perspectives or design new molecules and materials with unique properties. Materials Design. It is well established that molecular approaches to crystal structure design can lead to new materials with desirable properties (e.g. optical). Despite this realization, an insufficient knowledge of factors that dictate crystal packing has hindered chemists from designing molecules that assemble to form functional solids, a priori, with predictable properties. This problem of crystal structure design, referred to as a problem of crystal engineering, is similar to solution phase organic synthesis in that chemists must plan routes, involving structural units known as synthons, to targeted, functional molecular systems. However, whereas solution phase organic synthesis is at a stage where synthetic routes are being reexamined to reduce steps for atom economy, the field of rational solid state design is at a stage where synthons are beginning to be identified. Of the properties that may be exploited for the design of molecular solids, it is solid state reactivity, in the form of bimolecular reactions, that we are studying. Such an approach to synthesis holds great promise for the designed, solvent-free synthesis of molecules, and materials, available either in low yields, as part of mixtures, or are completely inaccessible in the liquid phase. Unfortunately, however, most approaches to synthesis in the solid state are generally unreliable such that reaction homology, a concept central to the development of solution phase molecular synthesis, has been achieved with limited success. We are addressing this problem of reaction homology, using an approach that controls reactivity in solids by employing molecules that serve, via molecular recognition processes based on hydrogen bonds, as linear templates (see Figure 1), with the prospect that a reliable method for conducting reactions in the solid state will permit us to establish novel applications for the reactants (e.g. green chemistry), products (e.g. nanostructures), and materials (e.g. molecular devices). |
回复此楼» 猜你喜欢
中南大学易小艺课题组诚招2026申请-考核制博士生
已经有0人回复
-
海南师范大学招收化学博士（光电功能材料课题组招收博士研究生）
已经有10人回复
-
无机化学论文润色/翻译怎么收费?
已经有94人回复
» 本主题相关价值贴推荐，对您同样有帮助:
- 乙烯基吡啶+银 进行[2+2]光化学反应
已经有12人回复
- 求各位大神推荐关于金属有机材料MOFs的基础书籍或文献
已经有5人回复
- 无奈，不懂化学的领导，让我用两个化合物一起结晶，求支持
已经有17人回复
- 有没有朋友做过β-环糊精包结小分子，培养单晶的啊？拜求高手指点迷津啊~~
已经有7人回复
★
小木虫: 金币+0.5, 给个红包，谢谢回帖
小木虫: 金币+0.5, 给个红包，谢谢回帖