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dangguoju

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[交流] 上海应用技术学院胡隆胜实验室欢迎你

本校硕士研究生有一定的调剂名额，本课题组欲接收报考化学、化学相关专业，有制药工程、有机化学背景的考生优先。请有意愿者发邮件联系。
一、调剂应符合的条件
调剂考生初试成绩必须符合其第一志愿报考专业所在地区的复试分数线，必须考数学，不考数学的同学不能接收调剂。
二、调剂生政策
调剂考生（专业学位除外）均为享有普通奖学金。除享受学校的待遇外（每月500），课题组还提供生活补助（视个人努力程度而定，不过生活是没什么问题的）。
我校对所有2014年研究生制定了如下优惠政策：
      1、国家助学金及奖学金全覆盖，每生每年可获得国家助学金及奖学金在12000元/年左右（定向生
   除外），最高可获得16000元/年；
      2、进入实验室后，导师将根据研究生实验进展情况发放助研津贴，不低于300元/每月；
      3、学生入学后报销部分差旅费
三、联系方式
邮箱：dangguoju2008@163.com
四、导师简介
胡教授是上海应用技术学院制药工程方向的兼职教授，在外高桥开公司，生产基地在安徽芜湖，有比较多的实际经验。下面是胡教授的个人简历：

Longsheng Hu (胡隆胜）
上海静安长寿路999弄11号楼13层
手机: 156 0188 5001 Email:  Lawrencehulong@gmail.com

CORE COMPETENCIES主要能力

• Years of diversified drug product / process development experience: formulation, reformulation for dosage forms of solid, semi-solid (gel and emulsion), liquid, suspensions, ointments多年各种药物剂型：片剂，液体，悬浮液，膏等的开发和研究
• Drug delivery system development: transdermal, transbuccal, topical, controlled release多种药物给药系统：皮肤透吸，口腔膜透吸，皮肤表面吸收以及缓释的开发和研究
• Multiple international publications including scientific papers, patent and patent applications and book chapter多篇论文,专利及专利申请,书章节的发表
• Diversified education background in chemistry, chemical engineering and pharmaceutical science化学，化学工程以及药剂制药学的综合学科的教育背景
• Highly organized and effective interpersonal communication skills高度组织和有效的个人交流能力
• Fluent in English and Chinese流利的英文和中文

EDUCATION 教育背景

• Ph.D., Pharm. Science, Rutgers, The State University of New Jersey, Sept. 2003 to July, 2010 (worked as a part-time Ph.D student sponsored by Pfizer and J&J) 博士，美国新泽西州罗格斯大学药学院
• M.S., Chem. Engr., University of Cincinnati, OH 1992-1996硕士，美国辛辛那提大学化工系
• M.S., Pharm. Science, University of Cincinnati, OH 1994-1996硕士，美国辛辛那提大学药学院
• M.S., Chem. Engr, Sichuan University of China, China 1985-1988硕士，中国四川大学化工系
• B.S., Chemistry, Electronic University of Sci. & Tech. of China, Chengdu, China 1981-1985本科，中国电子科技大学材料应用化学系

CAREER SUMMARY

Oct. 2011 to Present, Director of Industrial Development, Sanofi – a French pharmaceutical Company, Shanghai, China。 2011年10月至今，工业事务部研发总监，法国赛诺菲药业公司，中国上海

• 负责俩个研发中心实验室的建立: 配方，工艺，分析实验室以及俩个研发团队的建设
• 负责俩个研发团队为中国市场中西处方、非处方药以及保健品的新产品的立项，研究及开发至上市. 主要产品包括: 糖尿病药, 护肝药-易善福, 小儿助消化药,女式阴道炎,小儿感冒, 镇痛药,　过敏药，维生素补充剂等.

• Responsible for setting up two development centers (lab and pilot labs in Hangzhou & Tangshan) with formulation, processing, and analytical functions
• Worked closely with a cross functional team of MKT, BD & Medical in NPD strategy, portfolio development and innovations
• Managed with a total of 12 FTCs (4 managers + 8 scientists) in formulation, processing, scale up, technical support to the manufacturing sites and analytical method development and Regulatory for TCM & OTC products  in Tangshan site
• Developed LRP (1 to 5 yrs) and managed day-to-day operations with annual budget of around 20 m RMB
• Developed two teams with good working ethic, professionalism, integrity, GMP/cGMP/ICH and global company compliance mind set
• Project initialization and management of more than 20 on-going projects including chemical drugs, TCM, OTC, Rx & Health Food such as liver protecting product Essentiale capsule, Diabetic products, Kids cough & cold liquid and granules, Allegra (180 & 120 mg tablet), Kids Digestive, Women Vaginal Treatment, Ibuprofen, Functional Food & Vitamin Supplements, etc.
• Effectively communicated and networked with Sanofi Global Industrial Development and Innovation team to bring global product development ideas to China team
• Effectively worked with external companies & KOLs for new product ideas and technologies as well as government recognized agency such as SH CDC for product testing, SFDAs and Dept. of Health to expedite product registration and filing processes
• Led the health food development team to gain two approvals of Women MV and Silver MV products from CFDA
• Led the TS RA team to successfully renew more than 20 product licenses

Dec. 2006-Oct. 2011, Johnson & Johnson Consumer HealthCare Division, Morris Plains, NJ, USA。 2006年12月至2011年10月，美国强生制药首席科学家，主要从事皮肤药,生发药,抗过敏药的研究和开发,美国新泽西州。

Principal Scientist

• Responsible for  leading technical activities in new product development, formulation, reformulation, research, new claims and identifying internal or external new technology for OTC Topical HealthCare franchises including Rogaine (hair regrowth), Neosporin (antibiotic) and Bengay (pain reliever),Zyrtec brands with dosage forms of liquid, suspension, foam, patch, ointment, cream
• Formulated a new emulsion based minoxidil prototype for efficacy in vivo study. Took lead in working effectively with internal colleagues at J&J Ethicon R&D to develop methodology and study protocol for conducting mice hair regrowth model study for new minoxidil formulations and worked effectively with J&J patent legal dept. to successfully file two USA patent applications for the new formulations
• Took a leading role in working with external companies to develop new liposome encapsulation technologies for topical healthcare minoxidil formulations
• Led extensive literature research and worked with medical/clinical and regulatory affair colleagues as well as outside experts in writing documents to Division of Dockets Management, FDA regarding Draft Bioequivalence Guidance on Minoxidil Aerosol, Foam/Topical 5% to request generic manufacturer of minoxidil Foam to conduct comprehensive clinical efficacy and safety studies
• Guided junior scientist and supervised three college interns to conduct formulation and research work for Rogaine brand

2002-2006, Pfizer Consumer HealthCare Division, Morris Plains, NJ, USA
Senior Scientist美国辉瑞制药高级科学家，主要从事皮肤药,生发药,抗过敏药的研究和开发,美国新泽西州。

• Responsible for formulation, reformulation, new product development, research, new claims and identifying internal or external new technology for OTC HealthCare franchise including Benadryl (allergy, anti-itch), Rogaine (hair regrowth), Hydrocortisone, Neosporin (antibiotic), Zyrtec and Bengay (pain reliever)
• Worked with a cross-functional team including medical/clinical affair, regulatory, process engineering, analytical, micro, stability, marketing, contract manufacturing to ensure successful clinical trial studies, CMC and NDA filing and the launch of Rogaine (minoxidil) Foam product
• Identified Novasome/Liposome technology from an external source and applied it in Lubriderm new product development with therapeutic benefits of reducing itching and minimizing eczema
• Reformulated and developed pilot plant and manufacturing scale up processes for Hydrocortizone launch
• Led the development of pilot plant and manufacturing scale up processes for new minoxidil gel formulation
• Supported the launch of Neosporin Scare Reduction Patch product
• Supervised three college interns to conduct formulation and research work for Rogaine brand

1996-2002, Avlon-Rani Corp., Chicago, IL, USA
Senior Scientist / Formulation Group Leader 美国芝加哥Avlon-Raani公司科学家及产品开发组组长

• Responsible for  OTC oral and topical drug product and process development for: Cough Suppressant (Dextromethorphan HBr), Nasal Decongestant (Phenylephrine HCl), Expectorant (Guaifensin), Pain Reliever (Ibuprofen, Ketoprofen), Medicated Throat Lozenges (menthol, benzocaine), Vitamin A, B, C and E, medicated skin care products such as acne treatment, etc.  in the dosage forms of solid, liquid/suspension, emulsion and liposome
• Supervised three formulators

1992-996, University of Cincinnati, Cincinnati, OH, USA
美国辛辛那提大学化工和药学院研究生
●  Graduate student in Chemical Engineering and Pharmaceutical Science
● Conducted research in preparation and characterization of prolonged release of Chloroprophenpyridamine tablet using wet granulation

1988-1992, Yunnan Institute of Technology, Kunming, Yunnan, China
Lecturer of Chemical Engineering Dept. 讲师，教研室主任, 云南工学院化工系
• 教化工热力学,科技英语
• 管理教研室的课程安排等

Professional Trainings

▪ GMP, cGMP, Medical Device, CMC, NDA, and ANDA/SNDA
▪ Project Management, Leadership Behaviour and Business Writing courses
▪ Patent Law, Emulsion / Suspension Technology, and FDA CTD/CMC format courses

Publications
▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Hair growth and/or regrowth compositions. McNeil-PPC Sep, 6 2012: US Patent 20120225898
▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Hair growth and/or regrowth compositions. McNeil-PPC Sep, 6 2012: US Patent 20120225897
▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Hair growth and/or regrowth compositions. McNeil-PPC Sep, 6 2012: US Patent 20120225897
▪ Bozena Michniak-Kohn, Longsheng Hu, Enhanced Transbuccal Drug Delivery System and Compositions, US Provisional Patent Application 61/386.001 and International Application No. PCT/US2011/001645, Sept. 23, 2011
▪ Ran Wei, Laurent Simon, Longsheng Hu, Bozena Michniak-Kohn, Effects of Iontophoresis and Chemical Enhancers on the Transport of Lidocaine and Nicotine Across the Oral Mucosa, Pharm Res 29(4):961-971 (2012)
▪ Sérgio M C SM Silva, Longsheng Hu,Bozena B BB Michniak-Kohn, A combination of nonionic surfactants and iontophoresis to enhance the transdermal drug delivery of ondansetron HCl and diltiazem HCl.  Eur J Pharm Biopharm 80(3):663-73 (2012)
▪ Longsheng Hu, Sérgio MC Silva,Bozena B Michniak-Kohn, Transdermal and transbuccal drug delivery systems: Enhancement using iontophoretic and chemical approaches  Int J Pharm 421(1):53-62 (2011)
▪ Longsheng Hu, B.B. Michniak-Kohn, Enhanced Transbuccal Delivery of Ondansetron HCl, US Provisional Patent Application, 2010
▪ Longsheng Hu, B.B. Michniak-Kohn, Enhanced Transbuccal Delivery of Ondansetron HCl, International J. of Pharm., 404 (2011) 66-74
▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Methods of Reducing Hair Loss and/or Facilitating Hair Growth and/or Regrowth. Mcneil-Ppc Jun, 16 2011: US 20110144142
▪ Longsheng Hu, Virginia Streusand Goldman, Josephine A Minerva, Susan Wendling: Hair Growth and/or Regrowth Compositions. Mcneil-Ppc Jun, 16 2011: US 20110144141
▪ Longsheng Hu, P. Batheja, V. Meidan, B. B. Michniak-Kohn, Chapter 4, Iontophoretic Transdermal Drug Delivery,  Handdbook of Non-Invasive Drug Delivery Systems, Elsevier, Page 95-114, 2010
▪ P. Batheja, D. Kaushik, Longsheng Hu and B.B Michniak-Kohn, Transdermal Iontophoresis, Transdermal Delivery, Drug Delivery, Pages 46-48, 2007
▪ Longsheng Hu, B. B. Michniak-Kohn, Enhanced In Vitro Transbuccal Delivery of Ondansetron HCl, accepted for 2010 AAPS Poster Presentation
▪ Longsheng Hu, B. B. Michniak-Kohn, , A Comparison of In Vitro Transdermal and Transbuccal Drug Delivery Systems using Nicotine Hydrogen Tartrate, accepted for 2010 AAPS Poster Presentation
▪ Longsheng Hu, B. B. Michniak-Kohn, The Effects of Chemical Enhancers and Iontophoresis on In Vitro Transdermal Delivery of Lidocaine HCl, accepted for 2010 AAPS Poster Presentation
▪ S.M.C. Silva, Longsheng Hu, J.J.S. Sousa, A.C.C. Pais, B. Michniak-Kohn, Enhancement strategies to improve the transdermal drug delivery of ondansetron hydrochloride: a combination of chemical penetration enhancers with iontophoresis, accepted for 2010 AAPS Poster Presentation
▪ S.M.C. Silva, Longsheng Hu, J.J.S. Sousa, A.C.C. Pais, B. Michniak-Kohn, Non ionic surfactants as chemical permeation enhancers for the transdermal of diltiazem hydrochloride: in vitro permeation studies and cytotoxicity assessment, accepted for 2010 AAPS Poster Presentation
▪ Ali N Syed, Wagdi W Habib, Longsheng Hu: Hair brightening system. Avlon Dec, 28 1999: US Patent 6007585
欢迎对制药工程有兴趣的青年报考研究生。

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