| 查看: 6634 | 回复: 2 | |||
| 当前主题已经存档。 | |||
[交流]
IC50，CC50，EC50的意义?
|
|||
|
IC50，CC50，EC50的意义我已经查了好多,可是总是有不同的说法，搞的我自己也糊涂了！不知道是否有明确的定义！ 希望朋友们能帮助一下，谢谢 |
回复此楼» 猜你喜欢
面上项目filecode邪修
已经有3人回复
-
应该是93bebmhtak前后十一个字符比较关键
已经有13人回复
-
关于代码变化问题，想知道的进来
已经有20人回复
-
这样的filecode谁见过
已经有21人回复
-
filecode与中标关系的预测
已经有5人回复
-
fileCode有新解读？
已经有18人回复
-
关于filecode，很负责任的告诉大家
已经有7人回复
-
【2027博士申请】纳米药物递送方向
已经有5人回复
-
关于豆爷回答的JTJC与%2F数量
已经有7人回复
-
2026国自然放榜时间
已经有3人回复
yalefield
金虫 (文坛精英)
老汉一枚
- 应助: 129 (高中生)
- 贵宾: 0.17
- 金币: 21238.9
- 散金: 3440
- 红花: 66
- 帖子: 12101
- 在线: 759.1小时
- 虫号: 96063
- 注册: 2005-10-07
- 专业: 高等教育学
- 管辖: 计算模拟
2楼2008-01-19 11:42:21
|
The CC50 represents the concentration of drug that is required for 50% cell kill (cytoxicity) of the uninfected cells. The IC50 represents the concentration of a drug that is required for 50% inhibition of viral replication in vitro . The EC50 represents the plasma concentration/AUC required for obtaining 50% of the maximum effect in vivo. IC50(From Wikipedia, the free encyclopedia) IC50, the half maximal inhibitory concentration, represents the concentration of an inhibitor that is required for 50% inhibition of things like an enzyme, a cell, a cell receptor or a microorganism. It's commonly used as a measure of drug effectiveness. Another measure of drug efficacy is EC50 which represents the concentration of a compound that is required to obtain 50% of the maximum effect. (Ex. EC100 would be the minimum concentration of a compound to obtain 100% of its effect). EC50 " Effect Concentration 50% " or concentration having 50% of effect compared to control |
3楼2008-01-20 02:08:42
100