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【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ bonny928: 金币+10, ★★★★★最佳答案, thanks~ 2014-02-09 21:37:51 jssxh: 金币+2, 谢谢参与,请继续关注本版块! 2014-02-10 09:49:15 jssxh: 检索EPI+1, 谢谢参与,请继续关注本版块! 2014-02-10 09:50:04
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Accession number: 20140117152833
Title: Novel cationic purpurinimides as potential photosensitizers: Design, synthesis and biological evaluation
Authors: Cui, Bing Cun1, 2; Yoon, Il2; Li, Jia Zhu2; Shim, Young Key2
Author affiliation: 1 College of Medicine, Hubei Polytechnic University, Huangshi, China
2 PDT Research Institute, School of Nano System Engineering, Inje University, Gimhae, Korea, Republic of
Corresponding author: Yoon, I.
Source title: Journal of Chemical and Pharmaceutical Research
Abbreviated source title: J. Chem. Pharm. Res.
Volume: 5
Issue: 11
Issue date: 2013
Publication year: 2013
Pages: 818-823
Language: English
E-ISSN: 09757384
Document type: Journal article (JA)
Publisher: Journal of Chemical and Pharmaceutical Research, 3/668 Malviya Nagar, Jaipur, Rajasthan, India
Abstract: A series of novel cationic purpurinimides which had long wavelength absorption were designed and synthesized using purpurin-18-N-aminoimides as starting materials. They demonstrated a considerable bathochromic shift of the major absorption band in the red region of the optical spectrum (705.8-718.9nm). Newly synthesized purpurinimides were screened for their antitumor activities, and showed enhanced PDT efficiency in A549 cells as compared to purpurin-18-N-aminoimide. The results showed the novel cationic purpurinimides could be considered a promising photosensitizer in photodynamic therapy.
Number of references: 20
Main heading: Photosensitizers
Controlled terms: Absorption spectroscopy - Drug products - Photodynamic therapy
Uncontrolled terms: A549 cells - Anti-tumor activities - Bathochromic shift - Biological evaluation - Chlorins - Long-wavelength absorption - Optical spectra - Purpurinimide
Classification code: 741 Light, Optics and Optical Devices - 801 Chemistry - 804.1 Organic Compounds
Database: Compendex
Compilation and indexing terms, © 2013 Elsevier Inc.
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