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[资源] Bioactive Natural Products: Detection,2nd Edition

Bioactive Natural Products: Detection, Isolation, and Structural Determination, Second Edition
By Steven M. Colegate, Russell J. Molyneux

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Publisher:  CRC
Number Of Pages:  624
Publication Date:  2007-12-14
ISBN-10 / ASIN:  0849372585
ISBN-13 / EAN:  9780849372582
Binding:  Hardcover

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Book Description:

Following the successful format of the first edition, Bioactive Natural Products: Detection, Isolation, and Structural Determination, Second Edition presents applications of the most recent techniques for the detection, isolation, and structural determination of bioactive natural products. This second edition features new case studies and illustrations that demonstrate practical applications of techniques covered in the book. Complementing the first edition, most of the contributors are new. The  text includes updates on bioactive chemical extraction, and NMR-based structure determination, and new contributions on liquid chromatography linked with mass spectrometry and NMR spectroscopy, dereplication approaches, assessment of source material for bioactive natural products and novel bioassay development.

Contents
Preface ...........................................................................................................................................vii
Editors ............................................................................................................................................ix
Contributors ...................................................................................................................................xi
Chapter 1 An Introduction and Overview ....................................................................................1
Steven M. Colegate and Russell J. Molyneux
Chapter 2 Detection and Isolation of Bioactive Natural Products .............................................. 11
Emilio L. Ghisalberti
Chapter 3 Nuclear Magnetic Resonance Spectroscopy: Strategies
for Structural Determination ......................................................................................77
Lindsay T. Byrne
Chapter 4 Quantitative NMR of Bioactive Natural Products ................................................... 113
Guido F. Pauli, Birgit U. Jaki, David C. Lankin, John A. Walter,
and Ian W. Burton
Chapter 5 Development and Application of LC-NMR Techniques
to the Identifi cation of Bioactive Natural Products .................................................. 143
Jean-Luc Wolfender, Emerson F. Queiroz, and Kurt Hostettmann
Chapter 6 Determination of the Absolute Confi guration of Bioactive Natural Products
Using Exciton Chirality Circular Dichroism ........................................................... 191
Hans-Ulrich Humpf
Chapter 7 Separation of Enantiomeric Mixtures of Alkaloids
and Their Biological Evaluation ...............................................................................209
Stephen T. Lee, Russell J. Molyneux, and Kip E. Panter
Chapter 8 Dereplication and Discovery of Natural Products by UV Spectroscopy ................. 221
Thomas O. Larsen and Michael A.E. Hansen
Chapter 9 Liquid Chromatography-Mass Spectrometry
in Natural Product Research ....................................................................................245
Ka-Wing Cheng, Feng Chen, and Mingfu Wang
Chapter 10 Application of High-Speed Countercurrent Chromatography
to the Isolation of Bioactive Natural Products .........................................................267
Huabin Li and Feng Chen
vi Contents
Chapter 11 Biosensing Approach in Natural Product Research .................................................299
Maria Minunni and Anna R. Bilia
Chapter 12 Anticancer Drug Discovery and Development from Natural Products ................... 323
Gordon M. Cragg and David J. Newman
Chapter 13 Sourcing Natural Products from Endophytic Microbes ........................................... 371
Gary Strobel and Uvidelio Castillo
Chapter 14 Isolation of Bioactive Natural Products from Myxobacteria ................................... 391
Makoto Ojika
Chapter 15 Naturally Occurring Glycosidase Inhibitors ............................................................407
Robert J. Nash
Chapter 16 Bioassay-Directed Isolation and Identifi cation of Antiafl atoxigenic
Constituents of Walnuts ........................................................................................... 421
Russell J. Molyneux, Noreen Mahoney, Jong H. Kim,
and Bruce C. Campbell
Chapter 17 Bioactive Peptides in Hen Eggs ................................................................................ 439
Yoshinori Mine and Icy D’Silva
Chapter 18 Biological Fingerprinting Analysis: Strategy for Screening Bioactive
Compounds in Traditional Chinese Medicines ........................................................ 459
Xingye Su, Hanfa Zou, Xiaoyuan Lei, Liang Kong, and Lianghai Hu
Chapter 19 Antimalarial Compounds from Traditionally Used Medicinal Plants ..................... 491
Lengo Mambu and Philippe Grellier
Chapter 20 Germination Stimulant in Smoke: Isolation and Identifi cation ............................... 531
Gavin R. Flematti, Emilio L. Ghisalberti, Kingsley W. Dixon,
and Robert D. Trengove
Chapter 21 Plant-Associated Toxins: Bioactivity-Guided Isolation, ELISA,
and LC-MS Detection .............................................................................................. 555
Steven M. Colegate
Index ............................................................................................................................................. 585
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