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Bioactive Natural Products: Detection,2nd Edition
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Bioactive Natural Products: Detection, Isolation, and Structural Determination, Second Edition By Steven M. Colegate, Russell J. Molyneux -------------------------------------------------------------------------------- Publisher: CRC Number Of Pages: 624 Publication Date: 2007-12-14 ISBN-10 / ASIN: 0849372585 ISBN-13 / EAN: 9780849372582 Binding: Hardcover -------------------------------------------------------------------------------- Book Description: Following the successful format of the first edition, Bioactive Natural Products: Detection, Isolation, and Structural Determination, Second Edition presents applications of the most recent techniques for the detection, isolation, and structural determination of bioactive natural products. This second edition features new case studies and illustrations that demonstrate practical applications of techniques covered in the book. Complementing the first edition, most of the contributors are new. The text includes updates on bioactive chemical extraction, and NMR-based structure determination, and new contributions on liquid chromatography linked with mass spectrometry and NMR spectroscopy, dereplication approaches, assessment of source material for bioactive natural products and novel bioassay development. Contents Preface ...........................................................................................................................................vii Editors ............................................................................................................................................ix Contributors ...................................................................................................................................xi Chapter 1 An Introduction and Overview ....................................................................................1 Steven M. Colegate and Russell J. Molyneux Chapter 2 Detection and Isolation of Bioactive Natural Products .............................................. 11 Emilio L. Ghisalberti Chapter 3 Nuclear Magnetic Resonance Spectroscopy: Strategies for Structural Determination ......................................................................................77 Lindsay T. Byrne Chapter 4 Quantitative NMR of Bioactive Natural Products ................................................... 113 Guido F. Pauli, Birgit U. Jaki, David C. Lankin, John A. Walter, and Ian W. Burton Chapter 5 Development and Application of LC-NMR Techniques to the Identifi cation of Bioactive Natural Products .................................................. 143 Jean-Luc Wolfender, Emerson F. Queiroz, and Kurt Hostettmann Chapter 6 Determination of the Absolute Confi guration of Bioactive Natural Products Using Exciton Chirality Circular Dichroism ........................................................... 191 Hans-Ulrich Humpf Chapter 7 Separation of Enantiomeric Mixtures of Alkaloids and Their Biological Evaluation ...............................................................................209 Stephen T. Lee, Russell J. Molyneux, and Kip E. Panter Chapter 8 Dereplication and Discovery of Natural Products by UV Spectroscopy ................. 221 Thomas O. Larsen and Michael A.E. Hansen Chapter 9 Liquid Chromatography-Mass Spectrometry in Natural Product Research ....................................................................................245 Ka-Wing Cheng, Feng Chen, and Mingfu Wang Chapter 10 Application of High-Speed Countercurrent Chromatography to the Isolation of Bioactive Natural Products .........................................................267 Huabin Li and Feng Chen vi Contents Chapter 11 Biosensing Approach in Natural Product Research .................................................299 Maria Minunni and Anna R. Bilia Chapter 12 Anticancer Drug Discovery and Development from Natural Products ................... 323 Gordon M. Cragg and David J. Newman Chapter 13 Sourcing Natural Products from Endophytic Microbes ........................................... 371 Gary Strobel and Uvidelio Castillo Chapter 14 Isolation of Bioactive Natural Products from Myxobacteria ................................... 391 Makoto Ojika Chapter 15 Naturally Occurring Glycosidase Inhibitors ............................................................407 Robert J. Nash Chapter 16 Bioassay-Directed Isolation and Identifi cation of Antiafl atoxigenic Constituents of Walnuts ........................................................................................... 421 Russell J. Molyneux, Noreen Mahoney, Jong H. Kim, and Bruce C. Campbell Chapter 17 Bioactive Peptides in Hen Eggs ................................................................................ 439 Yoshinori Mine and Icy D’Silva Chapter 18 Biological Fingerprinting Analysis: Strategy for Screening Bioactive Compounds in Traditional Chinese Medicines ........................................................ 459 Xingye Su, Hanfa Zou, Xiaoyuan Lei, Liang Kong, and Lianghai Hu Chapter 19 Antimalarial Compounds from Traditionally Used Medicinal Plants ..................... 491 Lengo Mambu and Philippe Grellier Chapter 20 Germination Stimulant in Smoke: Isolation and Identifi cation ............................... 531 Gavin R. Flematti, Emilio L. Ghisalberti, Kingsley W. Dixon, and Robert D. Trengove Chapter 21 Plant-Associated Toxins: Bioactivity-Guided Isolation, ELISA, and LC-MS Detection .............................................................................................. 555 Steven M. Colegate Index ............................................................................................................................................. 585 http://rapidshare.com/files/84160872/C084.rar |
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