²é¿´: 450  |  »Ø¸´: 1
±¾Ìû²úÉú 1 ¸ö ·­ÒëEPI £¬µã»÷ÕâÀï½øÐв鿴

liyan20220

ľ³æ (ÖøÃûдÊÖ)

[ÇóÖú] Çó·­ÒëÒ»¶ÎÖÐÎÄΪӢÎÄ

¿¹¾úëÄ£¨Antimicrobial peptides£©ÊÇÒ»Àà¾ßÓп¹¾ú»îÐԵĶÌëÄ£¬·Ö×ÓÁ¿ÔÚ1000-7000×óÓÒ£¬ÓÉ12-50¸ö°±»ùËá×é³É£¬¾ßÓйâÆ×¿¹¾úÐÔ£¬¿ÉɱËÀ¸ïÀ¼ÊÏÑôÐÔ¾ú¡¢¸ïÀ¼ÊÏÒõÐÔ¾ú¡¢Õæ¾úµÈ¡£¿¹¾úëÄORBKÊÇÀ´Ô´ÓÚÎÞÖ¸Å̳ôÍÞOdorrcma grahamiƤ·ô·ÖÃÚÎïµÄº¬16¸ö°±»ùËá²Ð»ùµÄÑôÀë×Ó¶àëÄ¡£¸Ã¶àëÄÊÇÒ»Àà»·ÐÎëÄ£¬²»½ö¾ßÓп¹¾ú»îÐÔ£¬»¹¾ßÓÐÎȶ¨µÄ´ÙÒȵºËØÊÍ·Å»îÐÔ¡£Ä¿Ç°»ñµÃ¿¹¾úëÄORBKµÄ·½·¨Ö»ÓÐÌáÈ¡ºÍºÏ³É£¬´ÓÎÞÖ¸Å̳ôÍÞÆ¤·ô·ÖÃÚÎïÖÐÌáÈ¡´æÔÚÌáÈ¡Á¿ÉÙµÄÆ¿¾±£¬¶ø»¯Ñ§ºÏ³É·¨³É±¾½Ï¸ß£¬ÒòΪ¸Ã¶àëĺϳÉÖл¹ÐèÒªÒ»¸ö»·»¯µÄ¹ý³Ì¡£ÔÚ±¾ÂÛÎÄÖУ¬ÎÒÃÇÀûÓûùÒò¹¤³Ì½áºÏH2O2Ñõ»¯µÄ·½·¨£¬³É¹¦»ñµÃÁË¿¹¾úëÄORBK£¬²¢¶Ô¸Ã¿¹¾úëĵÄ×÷ÓûúÖÆ½øÐÐÁË̽¾¿£¬Í¬Ê±£¬ÎÒÃÇ»¹¶Ô¿¹½áºÏ¸Ë¾ú¶àëÄD29P63ºÍPK34½øÐÐÁ˳õ²½Ñо¿¡£
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

RXMCDM

°æÖ÷ (ÎÄ̳¾«Ó¢)

ÓÅÐã°æÖ÷ÓÅÐã°æÖ÷ÓÅÐã°æÖ÷

¡¾´ð°¸¡¿Ó¦Öú»ØÌû

¡ï ¡ï ¡ï ¡ï ¡ï
liyan20220: ½ð±Ò+5, ·­ÒëEPI+1 2014-01-14 18:17:56
Antimicrobial peptides  are antimicrobial  peptides  with  molecular weight of about 1000-7000 and consists  of 12-50 amino acids whose  antibacterial spectrum include  Gram-positive bacteria, Gram-negative bacteria and fungi. ORBK antimicrobial peptides are cationic peptides derived from  Odorrcma grahami skin secretions containing 16 amino acid residues. A  cyclic peptide, ORBK antimicrobial peptides have not only  antimicrobial activity , but also a stable insulinotropic activity. Currently  ORBK antimicrobial peptide can only  be extracted  and synthesized .  The much smaller yields of Odorrcma grahami skin secretions extraction is a critical technical bottleneck  and  the cost of chemical synthesis  is  high  because it  requires a cyclic process . In this paper, we use a genetic engineering   combined H2O2 oxidation method, successfully obtained  ORBK antimicrobial peptides .The   mechanism of antimicrobial peptides has been explored  and  bacteria binding peptides D29P63 and PK34 were studied  also .
ÎÞÖ¸Å̳ôÍÞOdorrcma grahami ÇëºË¶Ô¡£
£¿
2Â¥2014-01-14 18:05:56
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
Ïà¹Ø°æ¿éÌø×ª ÎÒÒª¶©ÔÄÂ¥Ö÷ liyan20220 µÄÖ÷Ìâ¸üÐÂ
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] 0817 »¯Ñ§¹¤³Ì 299·ÖÇóµ÷¼Á ÓпÆÑо­Àú ÓжþÇøÎÄÕ +6 rare12345 2026-03-18 6/300 2026-03-18 14:16 by ÐÇ¿ÕÐÇÔÂ
[¿¼ÑÐ] 344Çóµ÷¼Á +5 knight344 2026-03-16 5/250 2026-03-18 12:39 by ѧԱHHvs9Y
[¿¼ÑÐ] ²ÄÁÏ£¬·ÄÖ¯£¬ÉúÎ0856¡¢0710£©£¬»¯Ñ§ÕÐÉúÀ² +3 Eember. 2026-03-17 9/450 2026-03-18 10:28 by Eember.
[¿¼ÑÐ] ²ÄÁÏÓ뻯¹¤Çóµ÷¼Á +6 Ϊѧ666 2026-03-16 6/300 2026-03-17 20:15 by peike
[¿¼ÑÐ] 328Çóµ÷¼Á£¬Ó¢ÓïÁù¼¶551£¬ÓпÆÑо­Àú +3 ÉúÎ﹤³Ìµ÷¼Á 2026-03-16 8/400 2026-03-17 19:03 by Wangjingyue
[¿¼ÑÐ] 308Çóµ÷¼Á +4 ÊÇLupa°¡ 2026-03-16 4/200 2026-03-17 17:12 by ruiyingmiao
[¿¼ÑÐ] 085600²ÄÁÏÓ뻯¹¤Çóµ÷¼Á +5 Ð÷ÐÒÓë×Ó 2026-03-17 5/250 2026-03-17 16:40 by laoshidan
[¿¼ÑÐ] 290Çóµ÷¼Á +6 ¿×Ö¾ºÆ 2026-03-12 11/550 2026-03-17 14:41 by ÖÜÖÛÖÛ77
[»ù½ðÉêÇë] ¹ú×Ô¿ÆÃæÉÏ»ù½ð×ÖÌå +6 iwuli 2026-03-12 7/350 2026-03-16 21:18 by sculhf
[¿¼ÑÐ] 326Çóµ÷¼Á +4 ŵ±´¶û»¯Ñ§½±êéê 2026-03-15 7/350 2026-03-16 17:11 by ŵ±´¶û»¯Ñ§½±êéê
[¿¼ÑÐ] 304Çóµ÷¼Á +3 ÂüÊâ2266 2026-03-14 3/150 2026-03-16 16:39 by houyaoxu
[¿¼ÑÐ] 080500£¬²ÄÁÏѧ˶302·ÖÇóµ÷¼ÁѧУ +4 ³õʶ¿ÉÀÖ 2026-03-14 5/250 2026-03-14 21:08 by peike
[¿¼ÑÐ] ²ÄÁϹ¤³Ì327Çóµ÷¼Á +3 xiaohe12w 2026-03-11 3/150 2026-03-14 20:20 by ms629
[¿¼ÑÐ] Öпƴó²ÄÁÏÓ뻯¹¤319Çóµ÷¼Á +3 ÃÏöβÄÁÏ 2026-03-14 3/150 2026-03-14 20:10 by ms629
[¿¼ÑÐ] 255Çóµ÷¼Á +3 Àî¼Î»Û£¬ 2026-03-12 4/200 2026-03-14 16:58 by ÓÐÖ»ÀêÅ«
[¿¼ÑÐ] ¿¼Ñе÷¼Á +4 ·Ò´ï46 2026-03-12 4/200 2026-03-13 16:04 by ruiyingmiao
[¿¼ÑÐ] ¹¤¿Æ²ÄÁÏ085601 279Çóµ÷¼Á +8 À§ÓÚÐdz¿ 2026-03-12 10/500 2026-03-13 15:42 by ms629
[¿¼ÑÐ] ²ÄÁÏ301·ÖÇóµ÷¼Á +5 Liyouyumairs 2026-03-12 5/250 2026-03-13 14:42 by JourneyLucky
[¿¼ÑÐ] һ־Ըɽ´ó07»¯Ñ§ 332·Ö ËÄÁù¼¶Òѹý ±¾¿ÆÉ½¶«Ë«·Ç Çóµ÷¼Á£¡ +3 ²»ÏëÀíÄã 2026-03-12 3/150 2026-03-13 14:18 by JourneyLucky
[ÂÛÎÄͶ¸å] Ͷ¸åÎÊÌâ 5+4 Ðǹâ²ÓÀÃxt 2026-03-12 6/300 2026-03-13 14:17 by god_tian
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û