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金虫 (小有名气)

应助: 0 (幼儿园)
金币: 945.7
散金: 8
红花: 7
帖子: 117
在线: 43.8小时
虫号: 1650056
注册: 2012-02-28
性别: GG
专业: 合成药物化学

[交流] DRUG DISCOVERY from Bedside to Wall Street

DRUG DISCOVERY
from Bedside to Wall Street
Tamas Bartfai, Ph.D.
&
Graham V. Lees, Ph.D.
1. THE ART OF PUTTINGA MOLECULE INTO MAN 3
2. RAISING AND RISING EXPECTATIONS 13
3. HISTORY IS GOOD TO KNOW 23
4. THE BETTERBETA-BLOCKER BARRIER
5. WHY SOME GOOD DRUGS DO NOT GET A CHANCE AND
WHY OTHERS FAIL
6. ABOUT THE ECONOMICS OF TARGET AND CLINICAL
CANDIDATE SELECTION
7. TARGET-BASED DRUG DISCOVERY: PARTI
8. CHANGES NEED TO BE MADE
9. TARGET-BASED DRUG DISCOVERY: PART II
10. “DRUGABLE” TARGETS
11. SO MANY DRUGS, S O FEW ENTITIES
12. HOW TO FIND A CANDIDATE DRUG
13. PRACTICALITIES: THE HOOPS AND HURDLES OF BIG PHARMA
14. PRACTICAL TRIALS FOR A BALANCED PORTFOLIO 141
15. HOW TO IMPROVE THE ODDS OF FINDING A SAFE DRUG THAT WORKS 145
16. THE TRIBULATIONS OF CLINICAL TRIALS
17. LINKING PUTATIVE TARGETS TO DISEASE STATES
18. MORE WAYS TO LOOK FOR TARGETS
19. THE BUSINESS BASICS (GENERAL)
20. ADDING VALUE IN A GROWTH INDUSTRY
21. WHAT’S THEMOST PROFITABLE APPROACH?
22. PHARMACOECONOMICS FOR BIOTECH
23. SHRINKINGVALUE OF TARGETS
24. ASSESSING COMPANY ASSETS? LOOK IN THE LIBRARY
25. TO MERGE OR NOT TO MERGE?
26. WORKING WITH THE FOOD AND DRUG ADMINISTRATION (FDA)
27. REGULATING REGULATORY REGIMENS RELIABLY
28. THE HYPOTHESIS IS: THERE IS A BETTERWAY
29. WHAT ARE “WE” ALL WORKING ON?
30. MORE TABLETS TAKEN PER DAY THAN MEALS SERVED:

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