| 查看: 234 | 回复: 0 | |||
| 当前主题已经存档。 | |||
[资源]
Drug Metabolism: Chemical and Enzymatic Aspects: Textbook Edition
|
|||
|
By Jack P. Uetrecht, William Trager, Publisher: Informa Healthcare Number Of Pages: 200 Publication Date: 2007-06-21 ISBN / ASIN: 1420061038 -------------------------------------------------------------------------------- Book Description: In order to understand drug metabolism at its most fundamental level, pharmaceutical scientists must be able to analyze drug compound structures and predict possible metabolic pathways in order to avoid the risk of adverse reactions that lead to the withdrawal of a drug from the market. This comprehensive textbook will aid in guiding students through the recognition of the chemical underpinnings of drug metabolism. While there are numerous resources available for understanding drug structure, and other texts relating to drug metabolism from a biological standpoint, there is no other resource currently available that links both the chemical and biological terminology together in a clear and concise language, written, to be accessible for use in the classroom, as an education tool for teaching drug development. Drug Metabolism: Chemical and Enzymatic Aspects explains, to teachers and students alike, how a drug is metabolized, the potential effects of the metabolites, extensive material to help understand drugmetabolism within a biological context, and practical problems and answers Contents Preface . . . . iii 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. Background for Nonchemists . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 3. Background for Chemists . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18 4. Oxidation Pathways and the Enzymes That Mediate Them . . . . . . . . . . . . . . . 33 5. Reductive Pathways . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 6. Hydrolytic Pathways . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120 7. Conjugation Pathways . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 8. Reactive Metabolites . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145 Practice Problems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 Answers to Practice Problems . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169 Index . . . . 175 http://www.91files.com/?B9ETE2XUJNC7J8BZ3HK9 |
回复此楼» 猜你喜欢
公共卫生335求调剂！
已经有0人回复
-
散金，时间戳，前后缀，心电图，医学面上，结果未知，立贴参考
已经有84人回复
-
中药学论文润色/翻译怎么收费?
已经有156人回复
-
公共卫生311求调剂
已经有0人回复
-
求调剂
已经有0人回复
-
免费的论文查重网站
已经有0人回复
-
305临床医学专业一志愿川北医学院求调剂
已经有0人回复
10