| 查看: 279 | 回复: 0 | ||
卧马藏刀木虫 (正式写手)
论坛精英
|
[求助]
基因多态性影响阿片类药物用量语段翻译，求助
|
|
Moreover, of the 112 subjects there were 45 wild-type homozygotes CC, 49 heterozygotes CT and 18 mutant homozygotes TT. The frequency of ABCB1 C3435T allele was 37.94%. The sequencing results of the ABCB1 rs1045642 were showed in Figure 1. The distribution of ABCB1 C3435T allele was in Hardy-Weinberg equilibrium (p>0.05). The following study had failed to reveal any significant difference in 24h-opioids doses among the subjects carrying various ABCB1 allele phenotype (Table 4). Compared with the CC/CT phenotype, the subjects with TT homozygotes tended to require lower opioids intake dosage, but no significant statistical differences were observed (p=0.0057). However, when we measured using weight-surface area-adjusted-24h- opioids doses instead, the dosages of opioids administrated for the TT homozygotes was 0.60 ± 0.49 mg and significantly lower than those with CC/CT phenotypes (1.08 ± 0.88 mg , p=0.028). 本段文献主要讲的是ABCB1基因多态性对24小时阿片类药物用量（镇痛）的影响，“ weight-surface area-adjusted-24h- opioids doses”，这个名词不是很理解，“However, when we measured using weight-surface area-adjusted-24h- opioids doses instead, the dosages of opioids administrated for the TT homozygotes was 0.60 ± 0.49 mg and significantly lower than those with CC/CT phenotypes ”这句话我也翻译的很不到位（个人感觉），请大神们多多指教 |
回复此楼» 猜你喜欢
青椒八年已不青，大家都被折磨成啥样了？
已经有16人回复
-
退学或坚持读
已经有15人回复
-
免疫学博士有名额，速联系
已经有9人回复
-
国家基金申请书模板内插入图片不可调整大小?
已经有8人回复
-
多组分精馏求助
已经有6人回复
-
国家级人才课题组招收2026年入学博士
已经有6人回复
-
交叉科学部支持青年基金，对三无青椒是个机会吗？
已经有7人回复
