ľ³æ (ÖøÃûдÊÖ)
ÂþÂþ³¤Â·¶ÀÐÐÕß ![]()
|
¡¾´ð°¸¡¿Ó¦Öú»ØÌû
¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï ¡ï oven1986: ½ð±Ò+1, ¸ÐлӦÖú£¬¹ÄÀøÒ»Ï¡£ 2013-09-26 18:56:19 chq276617806(oven1986´ú·¢): ½ð±Ò+40, ´ú¿Û½áÌû£¬OK¡£ 2013-10-06 21:28:14 oven1986: ¼ìË÷EPI+1, ¸ÐлÄãµÄÓ¦Öú£¡ 2013-10-06 21:28:29
The New Cassane-Type Diterpenes from Caesalpinia minax
×÷Õß: Ma, GX (Ma, Guo-Xu)[ 1,2 ] ; Yuan, JQ (Yuan, Jing-Quan)[ 3 ] ; Cao, L (Cao, Li)[ 1,2 ] ; Yang, JS (Yang, Jun-Shan)[ 1,2 ] ; Xu, XD (Xu, Xu-Dong)[ 1,2 ]
À´Ô´³ö°æÎï: CHEMICAL & PHARMACEUTICAL BULLETIN ¾í: 60 ÆÚ: 6 Ò³: 759-763 ³ö°æÄê: JUN 2012
±»ÒýƵ´Î: 0 (À´×Ô Web of Science)
ÒýÓõIJο¼ÎÄÏ×: 19 [ ²é¿´ Related Records ] ÒýÖ¤¹ØÏµÍ¼
ÕªÒª: Four new cassane-type diterpenes, Neocaesalpin S (1), Neocaesalpin T (2), Neocaesalpin U (3), and Neocaesalpin V (4) were isolated from Caesalpinia minax HANCE together with seven known compounds Neocaesalpin A (5), Neocaesalpin K (6), Neocaesalpin L (7), Neocaesalpin M (8), Neocaesalpin 0 (9), Neocaesalpin MP (10), and Magnicaesalpin (11). Their structures were elucidated on the basis of 1D- and 2D-NMR, MS, and circular dichroism (CD) analysis. Compounds 1-4 were tested against liver cancer (HepG-2) and breast cancer (MCF-7), and showed mild antiproliferative activity.
Èë²ØºÅ: WOS:000304727000010
ÎÄÏ×ÀàÐÍ: Article
ÓïÖÖ: English
×÷Õ߹ؼü´Ê: Caesalpinia minax; cassane-type diterpene; antiproliferative activity
KeyWords Plus: CRISTA L.; BONDUC; SEEDS; ALCOHOLS; FABACEAE; HANCE
ͨѶ×÷ÕßµØÖ·: Xu, XD (ͨѶ×÷Õß) Peking Union Med Coll, Key Lab Bioact Subst & Resources Utilizat Chinese, Minist Educ, Inst Med Plant Dev, Beijing 100193, Peoples R China.
ÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ
Chinese Academy of Medical Sciences-Peking Union Medical College
µØÖ·: [ 1 ] Peking Union Med Coll, Key Lab Bioact Subst & Resources Utilizat Chinese, Minist Educ, Inst Med Plant Dev, Beijing 100193, Peoples R China
ÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ
Chinese Academy of Medical Sciences-Peking Union Medical College
[ 2 ] Chinese Acad Med Sci, Beijing 100193, Peoples R China
ÔöÇ¿×éÖ¯ÐÅÏ¢µÄÃû³Æ
Chinese Academy of Medical Sciences
Chinese Academy of Medical Sciences-Peking Union Medical College
[ 3 ] Guangxi Bot Garden Med Plant, Nanning 530023, Peoples R China
µç×ÓÓʼþµØÖ·: xdxu@implad.ac.cn
»ù½ð×ÊÖúÖÂл:
»ù½ð×ÊÖú»ú¹¹ ÊÚȨºÅ
technological large platform for comprehensive research and development of new drugs in the Eleventh Five-Year "Significant New Drugs Created" Science and Technology Major Projects 2009ZX09301-003
National Natural Science Foundation of China 30973626
Science and Technology Grant of Guangxi Province 0639039
Commonweal Academy and Institute of Central Authorities YZ-1-24
Innovation capacity-building in Guangxi Science and Technology Agency 0443002-2
[ÏÔʾ»ù½ð×ÊÖúÐÅÏ¢][Òþ²Ø»ù½ð×ÊÖúÐÅÏ¢]
The work was supported by the technological large platform for comprehensive research and development of new drugs in the Eleventh Five-Year "Significant New Drugs Created" Science and Technology Major Projects (No. 2009ZX09301-003). National Natural Science Foundation of China (No. 30973626), the Science and Technology Grant of Guangxi Province (No. 0639039) and special purpose of basic scientific research operation grant for Commonweal Academy and Institute of Central Authorities (No. YZ-1-24). Innovation capacity-building in Guangxi Science and Technology Agency (0443002-2).
³ö°æÉÌ: PHARMACEUTICAL SOC JAPAN, 2-12-15-201 SHIBUYA, SHIBUYA-KU, TOKYO, 150, JAPAN
Web of Science Àà±ð: Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy
Ñо¿·½Ïò: Pharmacology & Pharmacy; Chemistry
IDS ºÅ: 951NJ
ISSN: 0009-2363 |
|