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【答案】应助回帖
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The New Cassane-Type Diterpenes from Caesalpinia minax
作者: Ma, GX (Ma, Guo-Xu)[ 1,2 ] ; Yuan, JQ (Yuan, Jing-Quan)[ 3 ] ; Cao, L (Cao, Li)[ 1,2 ] ; Yang, JS (Yang, Jun-Shan)[ 1,2 ] ; Xu, XD (Xu, Xu-Dong)[ 1,2 ]
来源出版物: CHEMICAL & PHARMACEUTICAL BULLETIN 卷: 60 期: 6 页: 759-763 出版年: JUN 2012
被引频次: 0 (来自 Web of Science)
引用的参考文献: 19 [ 查看 Related Records ] 引证关系图
摘要: Four new cassane-type diterpenes, Neocaesalpin S (1), Neocaesalpin T (2), Neocaesalpin U (3), and Neocaesalpin V (4) were isolated from Caesalpinia minax HANCE together with seven known compounds Neocaesalpin A (5), Neocaesalpin K (6), Neocaesalpin L (7), Neocaesalpin M (8), Neocaesalpin 0 (9), Neocaesalpin MP (10), and Magnicaesalpin (11). Their structures were elucidated on the basis of 1D- and 2D-NMR, MS, and circular dichroism (CD) analysis. Compounds 1-4 were tested against liver cancer (HepG-2) and breast cancer (MCF-7), and showed mild antiproliferative activity.
入藏号: WOS:000304727000010
文献类型: Article
语种: English
作者关键词: Caesalpinia minax; cassane-type diterpene; antiproliferative activity
KeyWords Plus: CRISTA L.; BONDUC; SEEDS; ALCOHOLS; FABACEAE; HANCE
通讯作者地址: Xu, XD (通讯作者) Peking Union Med Coll, Key Lab Bioact Subst & Resources Utilizat Chinese, Minist Educ, Inst Med Plant Dev, Beijing 100193, Peoples R China.
增强组织信息的名称
Chinese Academy of Medical Sciences-Peking Union Medical College
地址: [ 1 ] Peking Union Med Coll, Key Lab Bioact Subst & Resources Utilizat Chinese, Minist Educ, Inst Med Plant Dev, Beijing 100193, Peoples R China
增强组织信息的名称
Chinese Academy of Medical Sciences-Peking Union Medical College
[ 2 ] Chinese Acad Med Sci, Beijing 100193, Peoples R China
增强组织信息的名称
Chinese Academy of Medical Sciences
Chinese Academy of Medical Sciences-Peking Union Medical College
[ 3 ] Guangxi Bot Garden Med Plant, Nanning 530023, Peoples R China
电子邮件地址: xdxu@implad.ac.cn
基金资助致谢:
基金资助机构 授权号
technological large platform for comprehensive research and development of new drugs in the Eleventh Five-Year "Significant New Drugs Created" Science and Technology Major Projects 2009ZX09301-003
National Natural Science Foundation of China 30973626
Science and Technology Grant of Guangxi Province 0639039
Commonweal Academy and Institute of Central Authorities YZ-1-24
Innovation capacity-building in Guangxi Science and Technology Agency 0443002-2
[显示基金资助信息][隐藏基金资助信息]
The work was supported by the technological large platform for comprehensive research and development of new drugs in the Eleventh Five-Year "Significant New Drugs Created" Science and Technology Major Projects (No. 2009ZX09301-003). National Natural Science Foundation of China (No. 30973626), the Science and Technology Grant of Guangxi Province (No. 0639039) and special purpose of basic scientific research operation grant for Commonweal Academy and Institute of Central Authorities (No. YZ-1-24). Innovation capacity-building in Guangxi Science and Technology Agency (0443002-2).
出版商: PHARMACEUTICAL SOC JAPAN, 2-12-15-201 SHIBUYA, SHIBUYA-KU, TOKYO, 150, JAPAN
Web of Science 类别: Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy
研究方向: Pharmacology & Pharmacy; Chemistry
IDS 号: 951NJ
ISSN: 0009-2363 |
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