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[交流] 壳聚糖微球的制备?

最近在做壳聚糖微球,有看到这样一篇文献:
Chitosan dissolved in 2% acetic acid was blown into an NaOH-methanol solution by compressed air through nozzles (0.15 mm diameter), and then the regenerated porous beads were washed by hot and cold water successively. From the nozzle
bead preparations having diameters ranging from 0.8 to 1.1 mm were produced.
不太理解这段话,溶解在乙酸中的壳聚糖加入到NaOH-甲醇中的作用是什么?具体怎么加进去?喷嘴直径0. 1 5mm是什么意思?用冷水热水洗的作用是什么?
求大家帮忙,谢谢
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