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Endothelial and mural cells share a basement membrane comprised of extracellular matrix proteins that form a sleeve around endothelial tubules. This basement membrane and the coat of mural cells prevent resident ECs from leaving their positions. At the on set of sprouting, ECs therefore must be liberated, a process requiring proteolytic breakdown of the basement membrane and detachment ofmural cells. [ Last edited by yin198716 on 2013-4-17 at 13:52 ] |
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°®ÓëÓêÏÂ: ½ð±Ò+1 2013-04-26 21:21:50
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Endothelial and mural cells share a basement membrane comprised of extracellular matrix proteins that form a sleeve around endothelial tubules. This basement membrane and the coat of mural cells prevent resident ECs from leaving their positions. At the onset of sprouting, ECs therefore must be liberated, a process requiring proteolytic breakdown of the basement membrane and detachment ofmural cells. ÄÚÆ¤Ï¸°ûºÍ±Úϸ°û¹²ÏíÓɰûÍâ»ùÖʵ°°××é³ÉµÄ»ùµ×Ĥ£¬ÕâÖÖ°ûÍâ»ùÖʵ°°×ÐγÉÎ§ÈÆÄÚÆ¤Ï¸¹ÜµÄÒ»²ãÌ׹ܡ£»ùµ×Ĥ¼°±Úϸ°ûµÄÍâ²ã×èÖ¹¹ÌÓеÄÄÚÆ¤Ï¸°û£¨ECs£©ÍÑÀëËüÃǵÄλÖá£ÔÚ¿ªÊ¼·¢Ñ¿Ê±£¬ÄÚÆ¤Ï¸°û£¨ECs£©±ØÐë±»ÊÍ·Å£¬Õâ¸ö¹ý³ÌÐèÒª»ùµ×ĤµÄµ°°×Ë®½â·Ö½â×÷Óü°±Úϸ°ûµÄ·ÖÀë¡£ СŮ²»²Å£¬Çë¶àÖ¸½Ì¡£ |

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