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Ó¢ÎÄÕªÒª: Biomimetic synthesis is one of important directions and current topics of modern biomineralization research,in which biological macromolecules induce the biomineralization of inorganic ion and further hierarchical self-assembly to form organic-inorganic nanocomposite materials. This project studied systemally that polypeptide molecules as templates mediated the synthesis of silica materials with a specific structure and morphology ,and the main study conclusions are as following: 1.The results of research reveal the mechanism and key factors of biomimetic synthesis of silica materials tailored by polypeptide. The polypeptide molecules mediated the nucleation, growth of inorganic ion to form the basic unit of self-assembly through the interaction of surface functional groups of polypeptide and inorganic ion. The basic unit formed further self-assembly to develop a specific structure and morphology of inorganic materials.2.We provide the preparation conditions of several specific structures and morphologies of silica materials, including spherical, rod-like, sheel-like and hollow sphere structure.3.Liquid atomic force microscopy (AFM) and laser scanning confocal microscopy (LSCM) with fluorescence tags were firstly performed to track in-situ and real-time the reaction process, and provide the direct experimental evidence for understanding the mechanism. The study results of the project provide the experimental and theoretical directive significance for the biomimetic synthesis of new function materials.
Ó¢ÎÄÖ÷Ìâ´Ê£º peptide moleculas; bio-materials of nanosilica; mediate; biomimetic synthesis; biomineralization;
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