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Silica nanoparticles coated with polyelectrolyte layers of carboxymethyl cellulose (CMC) or gelatin B, along with an oppositely charged peptide drug, were prepared using layer-by-layer self-assemblyand confirmed using QCM and zeta potential measurements. The peptide drug was assembled as a component of the multilayer walls. The release kinetics of the embedded peptide drug, Phor21-CG(ala), were determined. Up to 18% of the embedded Phor21-CG(ala) was released from the CMC multilayers over a period of 28 hours. |
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220chengeng: ½ð±Ò+1, ллӦÖú¡£ 2012-12-07 11:28:56
sltmac: ½ð±Ò+10, ·ÒëEPI+1 2013-02-21 09:15:02
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sltmac: ½ð±Ò+10, ·ÒëEPI+1 2013-02-21 09:15:02
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