应《网络安全法》要求，自2017年10月1日起，未进行实名认证将不得使用互联网跟帖服务。为保障您的帐号能够正常使用，请尽快对帐号进行手机号验证，感谢您的理解与支持！

24小时热门版块排行榜    

小木虫论坛-学术科研互动平台 » 生物医药区 » 生物科学 » 求助F-actin和β-actin的区别
132/2返回列表上一页12
查看: 12555  |  回复: 12
只看楼主 @他人 存档 新回复提醒 (忽略) 收藏    在APP中查看
本帖产生 2 个 BioEPI ，点击这里进行查看

JWGTI

新虫 (初入文坛)
★ ★ ★
看天: 金币+3, 鼓励 常来 2012-12-05 17:48:17
不好意思我有可能没讲清楚。
β-actin是可以存在在肌肉细胞中，但是它的主要作用不是在肌肉收缩上。F-actin的主要功能是肌肉收缩。
赞一下 回复此楼
11楼2012-12-05 14:18:16
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

myprayer

专家顾问 (著名写手)

优秀版主

【答案】应助回帖

★ ★ ★
感谢参与，应助指数 +1
wizardfan: 金币+3, BioEPI+1, 看上去是篇摘要，能把文章链接贴出就更好了，还有最好能高亮你的回答。最后活动期间给个EPI 奖励，以后多应助哈 2013-04-22 07:49:12
Background: Cells resident in certain hollow organs are subjected routinely to large transient stretches, including every
adherent cell resident in lungs, heart, great vessels, gut, and bladder. We have shown recently that in response to a transient
stretch the adherent eukaryotic cell promptly fluidizes and then gradually resolidifies, but mechanism is not yet understood.
Principal Findings: In the isolated human bladder smooth muscle cell, here we applied a 10% transient stretch while
measuring cell traction forces, elastic modulus, F-actin imaging and the F-actin/G-actin ratio. Immediately after a transient
stretch, F-actin levels and cell stiffness were lower by about 50%, and traction forces were lower by about 70%, both indicative
of prompt fluidization. Within 5min, F-actin levels recovered completely, cell stiffness recovered by about 90%, and traction
forces recovered by about 60%, all indicative of resolidification. The extent of the fluidization response was uninfluenced by a
variety of signaling inhibitors, and, surprisingly, was localized to the unstretch phase of the stretch-unstretch maneuver in a
manner suggestive of cytoskeletal catch bonds. When we applied an ‘‘unstretch-restretch’’ (transient compression), rather than
a ‘‘stretch-unstretch’’ (transient stretch), the cell did not fluidize and the actin network did not depolymerize.
Conclusions: Taken together, these results implicate extremely rapid actin disassembly in the fluidization response, and slow actin
reassembly in the resolidification response. In the bladder smooth muscle cell, the fluidization response to transient stretch occurs
not through signaling pathways, but rather through release of increased tensile forces that drive acute disassociation of actin.
β-actin作为一个亚基结构存在。前面有人说的有一点点道理，都是cytoskeletal里面的结构。
赞一下 回复此楼
12楼2012-12-06 22:14:45
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖

raylin

金虫 (初入文坛)

【答案】应助回帖

F-actin相当于聚合形式，
β-actin相当于单体。这样理解就容易了。
做WB的时候，裂解变性等都会使得F-actin和G-actin变为β-actin
赞一下 回复此楼
13楼2018-02-07 10:09:05
已阅   回复此楼   关注TA 给TA发消息 送TA红花 TA的回帖
相关版块跳转 我要订阅楼主 林夕梦 的主题更新
132/2返回列表上一页12
普通表情 龙 兔 虎 猫
最具人气热帖推荐 [查看全部] 作者 回/看 最后发表
[基金申请] filecode，4个jtjc了 +4 ziyangfang 2026-08-19 4/200 2026-08-19 10:23 by JChen2024
[基金申请] 时间戳变了，能看出什么问题？ +10 基诺咪客 2026-08-17 13/650 2026-08-19 10:22 by cssunt
[基金申请] 咱们一起用铁证分析2026国家社科基金中标与否 +8 启萌科技 2026-08-12 30/1500 2026-08-19 10:22 by 启萌科技
[基金申请] 今天基金会出结果吗？20260819 +6 kkkl_v 2026-08-19 6/300 2026-08-19 10:15 by zhangev
[基金申请] 今天放榜吗？ +11 布布和一二 2026-08-19 11/550 2026-08-19 10:06 by xter9665
[基金申请] 欢迎发来filecode的Mz6后的代码验证其规律 +52 医学老男孩 2026-08-13 114/5700 2026-08-19 09:38 by 医学老男孩
[基金申请] 什么时候开奖？ +6 CrisMessi 2026-08-18 6/300 2026-08-19 08:06 by Equinoxhua
[基金申请] 朋友圈看到的 +5 wangzilk 2026-08-18 6/300 2026-08-19 08:05 by luw152
[基金申请] 不应该看fileCode +8 且听虎啸 2026-08-12 10/500 2026-08-19 08:03 by luw152
[基金申请] 结合人工智能，周易传统文化，filecode打分制来了，3分以上希望很大。 +4 Tide man 2026-08-12 5/250 2026-08-19 07:41 by 201120518022
[基金申请] 重要消息，中午系统在维护 +10 yuleib84 2026-08-18 11/550 2026-08-19 07:30 by 羽毛枫f
[教师之家] 为什么余额宝的年化利率越来越低？主要原因有哪些？ +3 瞬息宇宙 2026-08-15 3/150 2026-08-18 21:40 by xiaohuixin
[基金申请] 明天放榜？ +5 Shxjjxjkx 2026-08-18 5/250 2026-08-18 18:14 by -大大大大大-
[基金申请] 今天维护系统维护 祝所有人 高中 +8 gjjjzhong 2026-08-18 9/450 2026-08-18 13:01 by 家与远方
[基金申请] 哪位老哥知道今年的国自然具体哪一天放榜？ +13 Ldrop2023 2026-08-13 16/800 2026-08-18 12:25 by 淀粉搬运工
[基金申请] filecode=后面第一个是大写字母 +8 wangze12014 2026-08-14 10/500 2026-08-17 17:05 by xter9665
[基金申请] 今天系统多次维护，明天很可能放榜！ +8 zju2000 2026-08-16 9/450 2026-08-17 12:20 by lmz0216
[精细化工] 招聘 金属平磨液，抛光液研发工程师 +3 小天0311 2026-08-14 3/150 2026-08-16 07:31 by H9PLUS
[基金申请] 各位道友，我要去昆明玩几天，回来见。 +7 Tide man 2026-08-14 8/400 2026-08-15 01:11 by arzu_hma
[基金申请] 重要来源：本周末出结果 +10 瞬息宇宙 2026-08-12 10/500 2026-08-13 15:46 by likettle
信息提示
关闭
请填处理意见
关闭