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[交流] 紫杉醇和紫杉酚的区别！算是普及一下...

However, because of the poor aqueous solubility and low therapeutic index of PTX, the clinical application is extremely limited. Presently, the only available formulation of PTX for clinical use is Taxol, containing Cremophor EL (polyethoxylated castor oil) and dehydrated ethanol in a 50:50 (v/v) ratio to solve solubility concerns and to increase its bioavailability. Unfortunately, Cremophor EL is associated with serious side effects such as hypersensitivity, nephrotoxicity, and neurotoxicity in many patients.(7)

（7）：Singla, A. K., Garg, A., and Aggarwal, D. Int. J. Pharm. 2002 235 179[CrossRef], [PubMed], [CAS]

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