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chenniuniu

金虫 (初入文坛)

应助: 0 (幼儿园)
金币: 1197.5
帖子: 9
在线: 4.4小时
虫号: 1120642
注册: 2010-10-12
性别: MM
专业: 基础兽医学

[求助] 大家帮忙翻译一段话吧

众所周知IBV易发生变异，变异株不断出现，使得现有的疫苗不能很好的控制该病，所以从现地分离株中致弱病毒是大势所趋。本文主要探讨一下病毒的变异机制及IBV致弱方法研究，为更好地防治该病奠定基础。IBV的变异机制主要是点突变、同源重组及免疫压力。这些变异可以引起毒株抗原变异和毒力变异，因此利用IBV的这些变异特性可以使病毒得以致弱。IBV的致弱方法主要有自然环境条件下的致弱和人工环境条件下的致弱以及分子生物学水平致弱。特别是利用现代分子生物学手段和反向遗传技术可以制备更安全、广谱、有效的弱毒疫苗，以克服传统弱毒疫苗的缺点。

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1楼2012-09-17 15:51:12

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xiaojiao_go2

银虫 (正式写手)

翻译EPI: 9
应助: 2 (幼儿园)
金币: 43.4
散金: 431
红花: 1
帖子: 369
在线: 30小时
虫号: 2004866
注册: 2012-09-16
专业: 古生物学和古生态学

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爱与雨下: 金币+1 2012-09-19 21:25:46
chenniuniu: 金币+20, 翻译EPI+1 2012-09-22 17:03:27

As is known to all IBV easy change, mutant appear constantly, making the current vaccine cannot very good control of the disease, so from separation of trees in attenuated virus is the trend of The Times. This article mainly discusses the virus variation mechanism and IBV attenuated method study, for the prevention and control of the disease better lay the foundation. The variation of IBV mechanism is mainly point mutation, homologous recombination and immune pressure. These mutations can cause strain antigen variation and virulence variation, so use of IBV these variation characteristics can make the virus have so that weak. IBV of attenuated method mainly have the natural environment conditions of attenuated and artificial environment conditions cause of the weak and the level of molecular biology attenuated. Especially the application of modern molecular biology method and reverse genetic technology can be preparation more security, broad spectrum and effective attenuated vaccine, in order to overcome the shortcomings of traditional attenuated vaccine.

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2楼2012-09-19 18:57:08

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lanhui_yang

金虫 (小有名气)

翻译EPI: 1
应助: 33 (小学生)
金币: 724.5
散金: 100
红花: 1
帖子: 185
在线: 88.4小时
虫号: 1482471
注册: 2011-11-08
性别: MM
专业: 色谱分析

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爱与雨下: 金币+1 2012-09-19 21:25:52

As is kown to all .IBV variate easliy ,since variation appearing ,the current vaccine can’t control the disease very well..as a result ,the attenuate virus are most affensive among existing IBV isolates.this article mainly discuss the variation mechanism of virus and attenuated method study , to ly in the foundation of disease prevention and treatment .mutation 、homologous recombinationvirus and immune presure are main variation mechanism . these variaton may lead to antigenicity and virulence change as well .so using the varibility of IBV can make the virus be attentuate itself . IBV attenuate mehod includes attenuation under natural environment 、 artificial environment and the level of molecular biology.especially by using of molecular biology method and Repercussions genetic technology ,much safer 、wider range 、more effective attenduate vaccine is produced,in order to overcome the shortcomings of traditional attenduate vaccine .

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