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爱与雨下: 金币+1 2012-09-19 21:25:46
chenniuniu: 金币+20, 翻译EPI+1 2012-09-22 17:03:27
As is known to all IBV easy change, mutant appear constantly, making the current vaccine cannot very good control of the disease, so from separation of trees in attenuated virus is the trend of The Times. This article mainly discusses the virus variation mechanism and IBV attenuated method study, for the prevention and control of the disease better lay the foundation. The variation of IBV mechanism is mainly point mutation, homologous recombination and immune pressure. These mutations can cause strain antigen variation and virulence variation, so use of IBV these variation characteristics can make the virus have so that weak. IBV of attenuated method mainly have the natural environment conditions of attenuated and artificial environment conditions cause of the weak and the level of molecular biology attenuated. Especially the application of modern molecular biology method and reverse genetic technology can be preparation more security, broad spectrum and effective attenuated vaccine, in order to overcome the shortcomings of traditional attenuated vaccine.
2楼2012-09-19 18:57:08
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