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Handbook of Carbohydrate Engineering
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Handbook of Carbohydrate Engineering Handbook of Carbohydrate Engineering Pages: The structure, function, and composition of many of the complex carbohydrates found in nature have been described by analytical chemistry and the composition of biosynthetic machinery used to build them has been revealed by advances in genome sequencing. This has set the stage for the active manipulation of carbohydrate structure and intervention in the glycosylation process. The Handbook of Carbohydrate Engineering provides an overview of the basic science, theory, methods, and applications of this broad, interdisciplinary field. It offers a cohesive, coordinated approach to carbohydrate engineering that will serve as an invaluable reference for laboratory researchers and students alike. Synopsis: Seventy-seven international researchers contribute 29 chapters providing an up-to-date overview of the basic science, theory, methods, and applications of carbohydrate engineering. Coverage includes the isolation, purification, and structural characterization of carbohydrates; the study of glycosylation in living cells; the exploitation of the "glycosylation machinery" for the production of complex carbohydrates in living cells; cell-free enzymatic methods for carbohydrate synthesis; chemical synthetic methods; industrial and biotechnological applications; applications in biomedicine and human health; and the types of carbohydrates梡olysaccharides, oligosaccharides, and monosaccharides. For practicing engineers and students in biology, chemistry, biochemistry, organic chemistry, chemical engineering, industrial research, and food science. Table of Contents: Ch. 1 Mammalian glycosylation : an overview of carbohydrate biosynthesis 1 Ch. 2 Patterning of lectins of vero and MDCK cells and influenza viruses : the search for additional virus/cell interactions 49 Ch. 3 O-acetyl sialic acids in parasitic diseases 71 Ch. 4 Congenital disorders of glycosylation 99 Ch. 5 Role of milk carbohydrates in preventing bacterial adhesion 141 Ch. 6 Structural characterization of glycosaminoglycans 177 Ch. 7 Carrageenans : structural and conformational studies 211 Ch. 8 Computational modeling in glycosylation 247 Ch. 9 Biosynthetic pathways for differential expression of functional chondroitin sulfate and heparan sulfate 289 Ch. 10 Large-scale production of oligosaccharides using engineered bacteria 325 Ch. 11 Fructan biosynthesis in genetically modified plants 339 Ch. 12 Chinese hamster ovary (CHO) glycosylation mutants for glycan engineering 371 Ch. 13 Biochemical engineering of sialic acids 387 Ch. 14 Glycosylation in native and engineered insect cells 407 Ch. 15 N-glycan engineering in yeasts and fungi : progress toward human-like glycosylation 431 Ch. 16 Bacterial capsules : a route for polysaccharide engineering 479 Ch. 17 Chemo-biological approach to modification of the bacterial cell wall 495 Ch. 18 Engineering bacterial biopolymers for the biosorption of heavy metals 507 Ch. 19 Treatment of wastewaters with the biopolymer chitosan 535 Ch. 20 The role of glycosylation in engineered antibodies 563 Ch. 21 Recent developments in the synthesis of oligosaccharides by hyperthermophilic glycosidases 587 Ch. 22 Modification of plant cell wall polysaccharides using enzymes from Aspergillus 613 Ch. 23 [beta]-glucosidases from filamentous fungi : properties, structure, and applications 645 Ch. 24 Sialic acids and sialylmimetics : useful chemical probes of sialic acid-recognizing proteins 687 Ch. 25 Engineering carbohydrate scaffolds into the side chains of amino acids and use in combinatorial synthesis 749 Ch. 26 Effects of short- and long-chain fructans on large intestinal physiology and development of preneoplastic lesions in rats 781 Ch. 27 Alginate as a drug delivery carrier 799 Ch. 28 Chitosan-based nonviral vectors for gene delivery 817 Ch. 29 Polysaccharides in tissue engineering applications 837 Download links: http://rapidshare.com/files/28261230/HCEng.rar.html or http://mihd.net/sdfxak or http://www.zshare.net/download/hceng-rar.html |
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