| 查看: 322 | 回复: 2 | ||
[求助]
求助
|
| 炎症检测中为什么检测IL-1β而不是IL-1α |
回复此楼» 猜你喜欢
311求调剂
已经有4人回复
-
304求调剂
已经有4人回复
-
354求调剂
已经有7人回复
-
321求调剂
已经有3人回复
-
274求调剂
已经有5人回复
-
281求调剂（0805）
已经有15人回复
-
085600材料与化工调剂 324分
已经有8人回复
-
能源材料化学课题组招收硕士研究生8-10名
已经有10人回复
-
267一志愿南京工业大学0817化工求调剂
已经有8人回复
-
328求调剂，英语六级551，有科研经历
已经有10人回复
【答案】应助回帖
★ ★
so善美: 金币+2 2013-07-24 17:50:39
so善美: 金币+2 2013-07-24 17:50:39
|
IL-1α is synthesized as a precursor protein and it is constitutively stored in a cytoplasm of cells with mesenchymal origin and in epithelial cells IL-1β is synthesized as a precursor form protein only after stimulation, in contrary to IL-1α. Its expression is induced by transcription factor NF-κB after exposure of innate immune cells to alarmins. For instance, after exposure of macrophages and dendritic cells to lipopolysaccharide (LPS), which binds to TLR4 and acts as pathogen-associated molecular pattern, that is another group of alarmins. [12][9]  |
2楼2013-07-22 09:57:21
3楼2013-07-24 17:46:58
