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【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ zhaoqiang0621: 回帖置顶 2012-05-25 16:11:28 zhaoqiang0621: 金币+25, ★★★很有帮助, 恩,认真翻译的,谢谢了 2012-05-25 18:43:11 爱与雨下: 金币+2 2012-05-27 16:36:45 sltmac: 翻译EPI+1 2012-06-18 07:33:14
【Abstract】
Objective: To prepare mexican tea herb (MTH)-gastric-floating tablets for improving their efficacy and reducing their toxic side effects.
Methods: The direct powder compression process was used to prepare gastric-floating tablets with hydrophilic matrix material of hydroxypropyl methyl cellulose (HPMC) and polyethylene oxide (PEO), initial floating agent of calcium carbonate and aided floating agent of behenyl triglyceride. The optimum formula was assessed by initial floating time, durative floating time and release rate. The factors influencing the drug release were also observed in this study.
Results: The in vitro results showed that the initial floating time was less than 3 minutes and the sustained floating time and the slow release time were up to 8 hours.
Conclusion: It suggests that MTH-gastric-floating tablets have a good floating and sustained-release effect. |
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