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1. Xu Gongxian, Modeling and Robust Control of Continuous Bioprocesses, 2010 Second International Conference on Computer Modeling and Simulation, Sanya, Hainan, China. 2. Xu Gongxian, An Iterative Strategy for Yield Optimization of Metabolic Pathways, 2010 Third International Joint Conference on Computational Sciences and Optimization, Huangshan, China. |
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Modeling and robust control of continuous bioprocesses ×÷Õß: Gongxian Xu À´Ô´³ö°æÎï: Proceedings of the 2010 Second International Conference on Computer Modeling and Simulation (ICCMS 2010) Ò³: (vol.2) 63-6 ³ö°æÄê: 2010 DOI: 10.1109/ICCMS.2010.289 »áÒéÐÅÏ¢: 2010 Second International Conference on Computer Modeling and Simulation (ICCMS 2010) Sanya, Hainan, China, 22-24 Jan. 2010 ÕªÒª: This paper deals with the problem of robust control for continuous bioprocesses. According to the material balance equations of continuous bioprocesses, a uniform framework for mathematical modeling of this class of processes is first presented. Then a robust controller is designed by using the Hinfin mixed sensitivity method for the bioprocesses. Finally, the proposed Hinfin control strategy is applied to bio-dissimilation process of glycerol to 1, 3-propanediol. Simulation results are given which show that the designed robust controller ensures the system has a favourable robust tracking performance. Èë²ØºÅ: 11168464 ÎÄÏ×ÀàÐÍ: Conference Paper ÓïÖÖ: English ´¦ÀíÀàÐÍ: Theoretical or Mathematical ÊÜ¿ØË÷Òý: biotechnology; control system synthesis; H infin control ; organic compounds; process control; robust control ·ÇÊÜ¿ØË÷Òý: robust control; continuous bioprocesses; material balance equations; Hinfin mixed sensitivity method; Hinfin control strategy; glycerol bio-dissimilation process; robust tracking performance; mathematical modeling; 1,3-propanediol ·ÖÀà´úÂë: C3350G Control applications in chemical and oil refining industries; C1330 Optimal control; C1320 Stability in control theory; C1310 Control system analysis and synthesis methods; E3628 Biotechnology industry; E1525 Industrial processes; E1550 Control technology and theory ¹ú¼ÊרÀû·ÖÀà: C12; G05B17/00 ×÷ÕßµØÖ·: Gongxian Xu; Dept. of Math., Bohai Univ., Jinzhou, China. ³ö°æÉÌ: IEEE, Piscataway, NJ, USA ²Î¿¼ÎÄÏ×Êý: 10 U.S. Copyright Clearance Center ´úÂë: 978-0-7695-3941-6/09/$26.00 ±ê×¼ÊéºÅ: 978-1-4244-5642-0 |
2Â¥2012-04-25 21:45:51
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An Iterative Strategy for Yield Optimization of Metabolic Pathways ×÷Õß: Gongxian Xu ±àÕß: Lean Yu; Yingwen Song; Wai-Ki Ching; Shouyang Wang; Lai, K.K. À´Ô´³ö°æÎï: Proceedings of the Third International Joint Conference on Computational Sciences and Optimization (CSO 2010) Ò³: (vol.2) 268-9 ³ö°æÄê: 2010 DOI: 10.1109/CSO.2010.225 »áÒéÐÅÏ¢: Third International Joint Conference on Computational Sciences and Optimization (CSO 2010) Huangshan, China, 28-31 May 2010 ÕªÒª: This paper addresses product yield optimization of metabolic pathways represented by the generalized mass action (GMA) systems. In most cases nonconvex yield optimization problems with GMA models cannot be transformed into convex optimization problems through geometric programming, but an iterative strategy can be used to compute the optimal solution by solving a series of geometric programming. The presented iterative strategy is applied to the fermentation pathway in Saccharomyces cerevisiae and shown to the effectiveness of the method. Èë²ØºÅ: 11494428 ÎÄÏ×ÀàÐÍ: Conference Paper ÓïÖÖ: English ´¦ÀíÀàÐÍ: Theoretical or Mathematical ÊÜ¿ØË÷Òý: biological techniques; biology computing; fermentation; geometric programming; microorganisms ·ÇÊÜ¿ØË÷Òý: metabolic pathway yield optimization; generalized mass action systems; nonconvex yield optimization problems; geometric programming; fermentation pathway; Saccharomyces cerevisiae ·ÖÀà´úÂë: A8780 Biophysical instrumentation and techniques; C7330 Biology and medical computing; C1180 Optimisation techniques ¹ú¼ÊרÀû·ÖÀà: G06F19/00 ×÷ÕßµØÖ·: Gongxian Xu; Dept. of Math., Bohai Univ., Jinzhou, China. ³ö°æÉÌ: IEEE Computer Society, Los Alamitos, CA, USA ²Î¿¼ÎÄÏ×Êý: 6 U.S. Copyright Clearance Center ´úÂë: 978-0-7695-4030-6/10/$26.00 ±ê×¼ÊéºÅ: 978-1-4244-6812-6 |
3Â¥2012-04-25 21:51:56
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4Â¥2012-04-25 21:57:17
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