去CA检索即可
结果如下
Bibliographic Information
Processes for preparing cinacalcet hydrochloride crystal form I. Lifshitz-Liron, Revital; Avhar-Maydan, Sharon. (Teva Pharmaceutical Industries Ltd., Israel; Teva Pharmaceuticals USA, Inc.). PCT Int. Appl. (2006), 25pp. CODEN: PIXXD2 WO 2006127933 A1 20061130 Designated States W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA. Designated States RW: AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IS, IT, LU, MC, NL, PT, SE, TR, BF, BJ, CF, CG, CI, CM, GA, ML, MR, NE, SN, TD, TG. Patent written in English. Application: WO 2006-US20304 20060523. Priority: US 2005-684152P 20050523; US 2005-696981P 20050705; US 2005-697111P 20050706; US 2005-698613P 20050711; US 2005-701232P 20050720; US 2005-702918P 20050726; US 2005-706910P 20050809; US 2005-730050P 20051024; US 2005-732083P 20051031; US 2005-733008P 20051102; US 2005-734669P 20051107; US 2005-735126P 20051108; US 2005-738827P 20051121; US 2005-741787P 20051201; US 2005-750910P 20051215; US 2006-794804P 20060424; WO 2006-US20304 20060523; EP 2006-771214 20060523; JP 2007-522852 20060523. CAN 146:13204 AN 2006:1251817 CAPLUS
Patent Family Information
Patent No. Kind Date Application No. Date
WO 2006127933 A1 20061130 WO 2006-US20304 20060523
W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
RW: AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR, BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG, BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW, AM, AZ, BY, KG, KZ, MD, RU, TJ, TM
CA 2606099 A1 20061130 CA 2006-2606099 20060523
US 20070060645 A1 20070315 US 2006-440246 20060523
US 7294735 B2 20071113
US 20070099998 A1 20070503 US 2006-439570 20060523
US 7247751 B2 20070724
BR 2006005859 A 20071218 BR 2006-5859 20060523
EP 1883618 A1 20080206 EP 2006-771215 20060523
EP 1883618 B1 20091014
R: AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR
JP 2008507566 T 20080313 JP 2007-522852 20060523
JP 4638491 B2 20110223
EP 1975150 A1 20081001 EP 2008-12814 20060523
R: AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR
AT 445587 T 20091015 AT 2006-771215 20060523
ES 2334260 T3 20100308 ES 2006-771215 20060523
MX 2007000983 A 20070416 MX 2007-983 20070123
KR 2007083471 A 20070824 KR 2007-7001966 20070126
IN 2007DN08108 A 20080704 IN 2007-DN8108 20071019
CN 101180261 A 20080514 CN 2006-80017939 20071123
JP 2010280715 A 20101216 JP 2010-197123 20100902
Priority Application
US 2005-684152P P 20050523
US 2005-696981P P 20050705
US 2005-697111P P 20050706
US 2005-698613P P 20050711
US 2005-701232P P 20050720
US 2005-702918P P 20050726
US 2005-706910P P 20050809
US 2005-730050P P 20051024
US 2005-732083P P 20051031
US 2005-733008P P 20051102
US 2005-734669P P 20051107
US 2005-735126P P 20051108
US 2005-738827P P 20051121
US 2005-741787P P 20051201
US 2005-750910P P 20051215
US 2006-794804P P 20060424
WO 2006-US20304 W 20060523
EP 2006-771214 A3 20060523
JP 2007-522852 A3 20060523
Abstract
The invention provides processes for the prepn. of cinacalcet-HCl cryst. Form I. Cinacalcet was dissolved in DMF and treated with 1N HCl to give the cryst. form I of the hydrochloride.
Indexing -- Section 63-6 (Pharmaceuticals)
Alcohols, uses
Role: NUU (Other use, unclassified); USES (Uses)
(C1-5; processes for prepg. cinacalcet hydrochloride crystal form I)
Alcohols, uses
Ethers, uses
Role: NUU (Other use, unclassified); USES (Uses)
(C2-5; processes for prepg. cinacalcet hydrochloride crystal form I)
Aromatic hydrocarbons, uses
Hydrocarbons, uses
Ketones, uses
Role: NUU (Other use, unclassified); USES (Uses)
(C3-6; processes for prepg. cinacalcet hydrochloride crystal form I)
Hydrocarbons, uses
Role: NUU (Other use, unclassified); USES (Uses)
(C5-8; processes for prepg. cinacalcet hydrochloride crystal form I)
Crystal structure
(of cinacalcet hydrochloride forms)
Antisolvents
Crystal morphology
Crystal polymorphism
(processes for prepg. cinacalcet hydrochloride crystal form I)
Esters, uses
Role: NUU (Other use, unclassified); USES (Uses)
(processes for prepg. cinacalcet hydrochloride crystal form I)
60-29-7, Diethyl ether, uses
64-17-5, Ethyl alcohol, uses
67-56-1, Methanol, uses
67-63-0, IPA, uses
67-64-1, Acetone, uses
67-68-5, Dimethyl sulfoxide, uses
68-12-2, Dimethylformamide, uses
75-05-8, Acetonitrile, uses
108-88-3, Toluene, uses
109-66-0, Pentane, uses
110-19-0, Isobutyl acetate
110-54-3, Hexane, uses
110-82-7, Cyclohexane, uses
127-19-5, DMAc
142-82-5, Heptane, uses
872-50-4, N-Methylpyrrolidone, uses
1634-04-4, MTBE
Role: NUU (Other use, unclassified); USES (Uses)
(processes for prepg. cinacalcet hydrochloride crystal form I)
364782-34-3P, Cinacalcet hydrochloride
Role: PRP (Properties); SPN (Synthetic preparation); THU (Therapeutic use); BIOL (Biological study); PREP (Preparation); USES (Uses)
(processes for prepg. cinacalcet hydrochloride crystal form I)
226256-56-0, Cinacalcet
Role: RCT (Reactant); THU (Therapeutic use); BIOL (Biological study); USES (Uses); RACT (Reactant or reagent)
(processes for prepg. cinacalcet hydrochloride crystal form I)
Supplementary Terms
cinacalcet hydrochloride crystal form prepn
Citations
Iqbal, J; IDRUGS 2003, 6(6), 587
Anon; SUMMARY BASIS OF APPROVAL OF NEW DRUG APPLICATION #21-688 2004 |