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Naproxcinod (formely HCT 3012) Inflammation in osteoarthritis - phase 3 Naproxcinod is NicOx¡¯ lead product, in phase 3 clinical development for the treatment of the signs and symptoms of osteoarthritis. It is a unique nitric oxide-donating anti-inflammatory and the first of the CINOD class (COX-Inhibiting Nitric Oxide Donators). NicOx aims to develop naproxcinod as a powerful anti-inflammatory agent with no detrimental effects on blood pressure and good gastrointestinal tolerability and safety. Top-line results from the first phase 3 study were successful. This represents an important step towards NicOx¡¯ goal of making naproxcinod the drug-of-choice for osteoarthritis patients. |
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