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chuxuan

铜虫 (正式写手)

[求助] 求助一段英语翻译。。。急啊。。。

Amicetin, an antibacterial and antiviral agent, belongs to a group of disaccharide  nucleoside antibiotics featuring an α -(1→4)-glycoside bond in the disaccharide moiety.    In this study, the amicetin biosynthetic gene cluster was cloned from  Streptomyces  vinaceus-drappus  NRRL 2363 and localized on a 37 kb contiguous DNA region.  Heterologous expression of the amicetin biosynthetic gene cluster in  Streptomyces  livdians  TK64 resulted in the production of amicetin and its analogues, thereby  confirming the identity of the  ami -gene cluster.    In silico  sequence analysis revealed  that 21 genes were putatively involved in amicetin biosynthesis, including 3 for  regulation and transportation, 10 for disaccharide biosynthesis, and 8 for the  formation of amicetin skeleton by the linkage of cytosine, para-benzoic acid (PABA),  and the terminal (+)-α -methylserine moieties.    The inactivation of the benzoate-CoA  ligase gene  amiL and the N-acetyltransferase gene  amiF, led to two mutants, which  accumulated the same two compounds cytosamine and 4-acetamido-3-  hydroxybenzoic acid.  These data indicated that AmiF functioned as an amide  synthethase to link cytosine and PABA.    The inactivation of amiR, encoding an acyl  CoA-acyl carrier protein transacylase, resulted in the production of plicacetin and  norplicacetin, indicating AmiR to be responsible for attachment of the terminal  methylserine moiety to form another amide bond.  These findings implicated two  alternative strategies for amide bond formation in amicetin biosynthesis.

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lzhbao123

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金币这么少,内容这么多,30个金币差不多会有人帮助吧!
2楼2012-01-31 14:06:20
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zuodg

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有为青年

【答案】应助回帖

你是张长生课题组的吗,友霉素是我一个同学做的东西
要活的出彩
3楼2012-01-31 14:33:27
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chuxuan

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引用回帖:
: Originally posted by zuodg at 2012-01-31 14:33:27:
你是张长生课题组的吗,友霉素是我一个同学做的东西

能 否帮我翻译  翻译啊。。。我英语糟糕着。。。有友霉素这方面的资料可否共享下 啊。。。我不是做这课题的。。就是看看而已。
4楼2012-02-01 12:42:19
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