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Biophysical Chemistry of Proteins
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During undergraduate courses in biochemistry you learned what proteins do as enzymes, receptors, hormones, motors or structural components. The more interesting question, how proteins can achieve all these functions, is usually asked only in graduate courses, and in many cases it is a topic of ongoing research. Here I want to present an overviewof the methods used in such research projects, their possible applications, and their limitations. I have limited the presentation to a level where a general background in chemistry, physics, and mathematics is sufficient to follow the discussion. Quantum mechanics, where required, is treated in a purely qualitative manner. A good understanding of protein structure and enzymology is required, but these topics I have covered in a separate volume [44]. Apart from graduate training in protein science this book should also be useful as a reference for people who work with proteins. After studying this book you should be able to collaboratewith workerswho have the required instruments and use these methods routinely. You should also be able to understand papers which make use of such methods. However, before embarking on independent research using these methods you are directed to the literature cited for a more in-depth, more quantitative coverage. This book focuses on the biophysical chemistry of proteins. The use of nucleic acid-based methods [360], although in many cases very relevant and informative, is outside the scope of this text. Also only hinted at are modern approaches to computational biochemistry [20, 180, 231]. In the end, the models derived from such techniques have to be verified by experiments. If this book stimulates such studies, it has served its purpose.  |
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2012-01-06 13:03:00, 7.32 M
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3楼2012-01-06 16:04:04
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4楼2012-01-06 20:33:36
好资源！ 9楼2012-01-07 09:59:59
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jinhx872楼
2012-01-06 13:34
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五星好评 顶一下，感谢分享！
gene0015楼
2012-01-06 21:00
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五星好评 顶一下，感谢分享！
sjshvdc6楼
2012-01-06 21:33
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五星好评 顶一下，感谢分享！
2012-01-07 02:27
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五星好评 顶一下，感谢分享！
2012-01-07 09:59
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五星好评 顶一下，感谢分享！
wtiger10楼
2012-01-07 11:39
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五星好评 顶一下，感谢分享！
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2012-01-07 14:13
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五星好评 顶一下，感谢分享！
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2012-01-08 02:51
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五星好评 顶一下，感谢分享！
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2012-01-08 08:29
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五星好评 顶一下，感谢分享！
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2012-01-12 00:32
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五星好评 顶一下，感谢分享！
