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[×ÊÔ´] Chem Soc Rev×îÐÂ×ÛÊö£ºÄÉÃײÄÁ϶¾ÐÔ

Nanoscience has matured significantly during the last decade as it has transitioned from bench top
science to applied technology. Presently, nanomaterials are used in a wide variety of commercial
products such as electronic components, sports equipment, sun creams and biomedical applications.
There are few studies of the long-term consequences of nanoparticles on human health, but
governmental agencies, including the United States National Institute for Occupational Safety and
Health and Japan¡¯s Ministry of Health, have recently raised the question of whether seemingly
innocuous materials such as carbon-based nanotubes should be treated with the same caution
afforded known carcinogens such as asbestos. Since nanomaterials are increasing a part of everyday
consumer products, manufacturing processes, and medical products, it is imperative that both
workers and end-users be protected from inhalation of potentially toxic NPs. It also suggests that
NPs may need to be sequestered into products so that the NPs are not released into the atmosphere
during the product¡¯s life or during recycling. Further, non-inhalation routes of NP absorption,
including dermal and medical injectables, must be studied in order to understand possible
toxic effects. Fewer studies to date have addressed whether the body can eventually eliminate
nanomaterials to prevent particle build-up in tissues or organs. This critical review discusses the
biophysicochemical properties of various nanomaterials with emphasis on currently available
toxicology data and methodologies for evaluating nanoparticle toxicity
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  • ¸½¼þ 1 : Toxicity of nanomaterials .pdf
  • 2011-12-16 00:09:18, 3.16 M

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