| 查看: 305 | 回复: 3 | |||
| 当前主题已经存档。 | |||
[交流]
询问蛋白中的几个概念
|
|||
| 蛋白质中的zimm-brag模型跟go model 分别是什么概念 |
回复此楼» 猜你喜欢
AI 太可怕了，写基金时，提出想法，直接生成的文字比自己想得深远，还有科学性
已经有3人回复
-
有院领导为了换新车，用横向课题经费买了俩车
已经有9人回复
-
酰胺脱乙酰基
已经有13人回复
-
博士延得我，科研能力直往上蹿
已经有8人回复
-
同年申请2项不同项目，第1个项目里不写第2个项目的信息，可以吗
已经有4人回复
-
有时候真觉得大城市人没有县城人甚至个体户幸福
已经有10人回复
-
天津大学招2026.09的博士生，欢迎大家推荐交流（博导是本人）
已经有5人回复
-
CSC & MSCA 博洛尼亚大学能源材料课题组博士/博士后招生｜MSCA经费充足、排名优
已经有6人回复
-
遇见不省心的家人很难过
已经有22人回复
zs200311
荣誉版主 (著名写手)
感受浪漫，品味高雅
- 应助: 0 (幼儿园)
- 贵宾: 3.1
- 金币: 3486.8
- 散金: 4691
- 红花: 26
- 帖子: 2989
- 在线: 137.3小时
- 虫号: 253788
- 注册: 2006-05-21
2楼2007-01-14 12:26:51
IDname
捐助贵宾 (正式写手)
钢虫
- 应助: 0 (幼儿园)
- 金币: 3384.3
- 散金: 100
- 红花: 1
- 帖子: 355
- 在线: 8.3小时
- 虫号: 269131
- 注册: 2006-07-30
- 专业: 生物化学
★ ★ ★ ★ ★
zjm022243(金币+3):谢谢，能帮我翻译成中文么
zjm022243(金币+2):thank u
zjm022243(金币+3):谢谢，能帮我翻译成中文么
zjm022243(金币+2):thank u
|
Zimm-Bragg model http://www.answers.com/topic/zimm-bragg-model Go model is based on coarse-grained molecular dynamics on the residue level with the energy function biased towards the native binding structure (Go model). With the model, the underlying free-energy landscape of the protein binding can be further explored. Go model is a simplified realization of landscape theory. It emphasizes the role of topology and native structures in determining the dynamic mechanisms. The energy function is chosen according to the native binding complex structure. In other words, the interaction energies among native contacts are uniformly attractive (often scale to value 1) stabilizing the native complex structure and the interactions of the non-native contacts are simply chosen to be zero value of energy (no bias towards the native structure). The potential can be implemented on lattice or off lattice simulations. In protein folding studies, people have implemented the Go potential for lattice, and off lattice simulations at the residue and atomic level. In this proposal, we will apply the atomic level Go potentials to study the binding-folding coupling dynamics by performing off lattice simulations. The advantage of the off lattice over lattice simulations is that the details such as the local secondary structures can be explicitly studied. The advantage of the atomic over residue level Go Model simulations is that the details such as local side chain packing can be explicitly studied. In our investigation, we will adapt the atomic Go model from our folding studies to binding and perform simulations taking into account of the microscopic details. http://www.sunysb.edu/seawulfcluster/luqia.shtml [ Last edited by IDname on 2007-1-14 at 17:07 ] |
3楼2007-01-14 17:03:51
wjmed
木虫 (正式写手)
- 应助: 2 (幼儿园)
- 金币: 2795.1
- 红花: 8
- 帖子: 812
- 在线: 50.4小时
- 虫号: 96805
- 注册: 2005-11-07
- 性别: GG
- 专业: 化学生物学与生物有机化学
|
参考下文 林嘉平，周达飞。分子链构象变化对高分子液晶相行为的影响。高分子学报。1999（4） 全文链接 http://www.wanfangdata.com.cn/qi ... gfzx9904/990409.htm |
4楼2007-01-15 09:44:42