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- ·ÒëEPI: 386
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°®ÓëÓêÏÂ(½ð±Ò+2): 2011-10-23 17:09:24
ºÎÐñ(½ð±Ò+50, ·ÒëEPI+1): ºÇºÇ£¬ÎÒÒªÀ¶¡Îĵģ¬Ð»Ð»ÄãÁËŶ 2011-10-24 08:56:25
°®ÓëÓêÏÂ(½ð±Ò+2): 2011-10-23 17:09:24
ºÎÐñ(½ð±Ò+50, ·ÒëEPI+1): ºÇºÇ£¬ÎÒÒªÀ¶¡Îĵģ¬Ð»Ð»ÄãÁËŶ 2011-10-24 08:56:25
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Abstract: Objective: research on extractive of Americana Linn£¨Periplaneta americana£©inhibition function on tumor-bearing rats S180 sarcoma and anti-cancer immune mechanism. Methods: vaccinate KM rats with S180 cells on right fore oxter and continuously lavage the extractive of American Linn CII-3[50¡¢100¡¢200mg/(kg.d)] for 10 days. Observe the growth effect on S180 tumor by CII-3 and weigh rats immune organs to calculate the index of visceral organs. Use ELISA kit to test the concentration of vessel endothelium growth factor (VEGF) and tumor necrosis factor-¦Á (TNF-¦Á) in serum. Results: The extractive of American Linn had apparent inhibition effect on growth of S180 tumor. The tumor inhibition ratio of high, medium, and low dosage groups are 58.22%, 45.66%, and 35.37%. The extractive has protective function on rats immune organs and dramatically increases the concentration of VEGF and TNF-¦Á in serum. Conclusions: The extractive of American Linn can inhibit the growth of rats S180 tumor and the ways to resist tumor cells may be increasing concentrations of VEGF and TNF-¦Á in serum. ÄǸöÃÀÖÞ´óó¹ÓÐÓ¢ÓïºÍÀ¶¡Á½ÖÖ·Ò룬¿´LZ×Ô¼ºÐèÒªÄÄÖÖÁË¡£ |
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