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[求助]
急寻找wt black swiss 小鼠 50金币感谢
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实验需要远交系swiss black小鼠，有此小鼠信息的虫子们帮忙寻找一下，小鼠信息 Black Swiss TRADITIONAL OUTBRED MICE Has larger litters and nurtures young better than inbred pigmented strains • Homozygous for the same coat color loci as the C57BL/6 • Useful for germline test mating of targeted mutation chimeras created using 129 agouti Embryonic Stem (ES) cell lines Origin: The Black Swiss outbred model was developed by Dr. Carl Hansen of the NIH Genetic Resource. N:NIH Swiss outbred mice were backcrossed to a C57BL/6N inbred background to generate a hybrid mouse heterozygous for the agouti locus. The mice were backcrossed ten generations (N10) to eliminate the agouti and albino alleles. Taconic received NTac:NIHBS litters in 1991. The mice were derived by caesarean derivatio in 1992 and rederived by embryo transfer in 2005 and 2009. The Taconic Black Swiss is maintained in a closed barrier using a rotational breeding scheme to maximize reproductive performance and heterozygosity, however SNPs testing has confirmed that the model is only slightly heterozygous and thus considered a partially inbred model.. Color: Black Coat Color Loci: a |
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