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ʵÑéÐèÒªÔ¶½»Ïµswiss blackСÊó£¬ÓдËСÊóÐÅÏ¢µÄ³æ×ÓÃǰïæѰÕÒһϣ¬Ð¡ÊóÐÅÏ¢ Black Swiss TRADITIONAL OUTBRED MICE Has larger litters and nurtures young better than inbred pigmented strains • Homozygous for the same coat color loci as the C57BL/6 • Useful for germline test mating of targeted mutation chimeras created using 129 agouti Embryonic Stem (ES) cell lines Origin: The Black Swiss outbred model was developed by Dr. Carl Hansen of the NIH Genetic Resource. N:NIH Swiss outbred mice were backcrossed to a C57BL/6N inbred background to generate a hybrid mouse heterozygous for the agouti locus. The mice were backcrossed ten generations (N10) to eliminate the agouti and albino alleles. Taconic received NTac:NIHBS litters in 1991. The mice were derived by caesarean derivatio in 1992 and rederived by embryo transfer in 2005 and 2009. The Taconic Black Swiss is maintained in a closed barrier using a rotational breeding scheme to maximize reproductive performance and heterozygosity, however SNPs testing has confirmed that the model is only slightly heterozygous and thus considered a partially inbred model.. Color: Black Coat Color Loci: a |
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sheryl99
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2Â¥2011-08-08 14:28:04
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silicare(½ð±Ò+1): 2011-08-09 11:36:36
sheryl99(½ð±Ò+2): ûÓÐÕÒµ½Å¶£¬²»¹ý·Ç³£¸Ðл°¡ 2011-08-09 16:37:17
silicare(½ð±Ò+1): 2011-08-09 11:36:36
sheryl99(½ð±Ò+2): ûÓÐÕÒµ½Å¶£¬²»¹ý·Ç³£¸Ðл°¡ 2011-08-09 16:37:17
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sheryl99
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4Â¥2011-08-09 11:42:07













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